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2.3.1.298: ultra-long-chain ceramide synthase

This is an abbreviated version!
For detailed information about ultra-long-chain ceramide synthase, go to the full flat file.

Reaction

an ultra-long-chain fatty acyl-CoA
+
a sphingoid base
=
an ultra-long-chain ceramide
+
CoA

Synonyms

(dihydro)ceramide synthase, ceramide synthase, ceramide synthase 3, CerS3, LASS3, LASS3-long, longevity assurance homologue 3, mammalian ceramide synthase 3, phytoceramide synthase, sphingoid base N-ultra-long-chain fatty acyl-coA transferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.298 ultra-long-chain ceramide synthase

Activating Compound

Activating Compound on EC 2.3.1.298 - ultra-long-chain ceramide synthase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
acyl-coenzyme A-binding protein
-
increases the activity of the enzyme by 7fold
-
additional information
-
high-speed liver cytosol from wild type mice activates enzyme activity, whereas cytosol from acyl-coenzyme A-binding protein knock-out mice does not
-