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2.1.1.357: [histone H3]-lysine36 N-dimethyltransferase

This is an abbreviated version!
For detailed information about [histone H3]-lysine36 N-dimethyltransferase, go to the full flat file.

Word Map on EC 2.1.1.357

Reaction

2 S-adenosyl-L-methionine +

a [histone H3]-L-lysine36
= 2 S-adenosyl-L-homocysteine +
a [histone H3]-N6,N6-dimethyl-L-lysine36

Synonyms

Ash1L, EC 2.1.1.43, H3K36 KMTase, H3K36 methyltransferase, H3K36-specific methyltransferase, histone H3 lysine 36 methyltransferase, KMT3B, KMT3C, Metnase, MMSET, NSD1, NSD2, NSD3, nuclear receptor SET domain containing protein 2, nuclear receptor-binding SET domain protein 2, SET, SETD2, SETMAR, Smyd2, Whsc1, WHSC1L1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase

Sequence

Sequence on EC 2.1.1.357 - [histone H3]-lysine36 N-dimethyltransferase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
SETMR_BOVIN
306
0
34254
Swiss-Prot
other Location (Reliability: 1)
SETMR_HUMAN
684
0
78034
Swiss-Prot
other Location (Reliability: 1)
SETMR_MOUSE
309
0
34417
Swiss-Prot
other Location (Reliability: 1)
SETMR_RAT
315
0
35030
Swiss-Prot
other Location (Reliability: 1)
SMYDL_CAEEL
507
0
57399
Swiss-Prot
other Location (Reliability: 2)
MES4_CAEEL
898
0
100065
Swiss-Prot
other Location (Reliability: 1)
MES4_DROME
1427
0
159028
Swiss-Prot
other Location (Reliability: 1)
NSD1_HUMAN
2696
0
296652
Swiss-Prot
other Location (Reliability: 1)
NSD1_MOUSE
2588
0
284084
Swiss-Prot
other Location (Reliability: 2)
NSD2_HUMAN
1365
0
152258
Swiss-Prot
other Location (Reliability: 2)
NSD2_MOUSE
1365
0
152253
Swiss-Prot
other Location (Reliability: 3)
ATXR7_ARATH
1423
0
158663
Swiss-Prot
other Location (Reliability: 5)
A0A6J8AFI7_MYTCO
157
0
18376
TrEMBL
other Location (Reliability: 5)
A0A812E2U6_SEPPH
1396
0
156002
TrEMBL
other Location (Reliability: 3)
A0A7R8CX31_LEPSM
715
0
81770
TrEMBL
Secretory Pathway (Reliability: 3)
A0A7R8D5U5_LEPSM
109
0
12953
TrEMBL
other Location (Reliability: 2)
A0A7R8H0P3_LEPSM
239
0
27547
TrEMBL
other Location (Reliability: 2)
A0A817FEX4_LEPSM
192
0
22335
TrEMBL
other Location (Reliability: 2)
A0A7R8CXQ5_LEPSM
457
0
53475
TrEMBL
other Location (Reliability: 5)
A0A7R8H552_LEPSM
255
0
28905
TrEMBL
other Location (Reliability: 4)
A0A7R8D7A1_LEPSM
523
0
60508
TrEMBL
other Location (Reliability: 2)
A0A7R8CHY6_LEPSM
418
0
47783
TrEMBL
other Location (Reliability: 1)
A0A7R8CXR9_LEPSM
604
0
69349
TrEMBL
other Location (Reliability: 2)
A0A7R8HD08_LEPSM
441
0
50787
TrEMBL
other Location (Reliability: 5)
A0A7R8CLK0_LEPSM
452
0
51834
TrEMBL
other Location (Reliability: 2)
A0A7R8CAH3_LEPSM
253
0
29668
TrEMBL
other Location (Reliability: 2)
A0A7R8CJC6_LEPSM
416
0
48159
TrEMBL
other Location (Reliability: 3)
A0A7R8CQJ3_LEPSM
243
0
26934
TrEMBL
other Location (Reliability: 2)
A0A7R8H0D9_LEPSM
579
0
65404
TrEMBL
other Location (Reliability: 1)
A0A7R8CNE9_LEPSM
264
0
30197
TrEMBL
other Location (Reliability: 2)
A0A7R8D4V9_LEPSM
1298
0
145623
TrEMBL
other Location (Reliability: 4)
A0A812ER50_SEPPH
359
6
39712
TrEMBL
Secretory Pathway (Reliability: 1)
A0A7R8CF44_LEPSM
551
0
63456
TrEMBL
other Location (Reliability: 3)
A0A7R8CIC7_LEPSM
505
0
58218
TrEMBL
other Location (Reliability: 1)
A0A812B7R7_SEPPH
467
0
53985
TrEMBL
other Location (Reliability: 2)
A0A7R8H6F5_LEPSM
509
0
59387
TrEMBL
other Location (Reliability: 1)
A0A7R8CEQ2_LEPSM
279
0
32058
TrEMBL
other Location (Reliability: 3)
A0A812BKV0_SEPPH
269
0
31323
TrEMBL
other Location (Reliability: 4)
A0A6J8E0Q9_MYTCO
317
0
36051
TrEMBL
other Location (Reliability: 2)
A0A7R8HC12_LEPSM
528
0
59856
TrEMBL
other Location (Reliability: 1)
A0A7R8CWI2_LEPSM
374
0
43944
TrEMBL
Mitochondrion (Reliability: 5)
A0A6J8ET49_MYTCO
194
0
23121
TrEMBL
other Location (Reliability: 2)
A0A7R8H766_LEPSM
231
0
26712
TrEMBL
Mitochondrion (Reliability: 2)
A0A7R8D1Q7_LEPSM
226
0
25699
TrEMBL
other Location (Reliability: 4)
A0A7R8H0P2_LEPSM
240
0
27745
TrEMBL
other Location (Reliability: 3)
A0A7R8CV37_LEPSM
478
0
54774
TrEMBL
other Location (Reliability: 1)
A0A812ATE7_SEPPH
155
0
18044
TrEMBL
other Location (Reliability: 2)
A0A7R8DCP7_LEPSM
390
0
45491
TrEMBL
other Location (Reliability: 2)
A0A7R8D9E7_LEPSM
501
0
57328
TrEMBL
other Location (Reliability: 2)
A0A812BN91_SEPPH
250
0
28584
TrEMBL
other Location (Reliability: 2)
A0A812E6Y8_SEPPH
1350
0
150923
TrEMBL
other Location (Reliability: 3)
A0A6J8D8G3_MYTCO
272
0
30739
TrEMBL
other Location (Reliability: 1)
A0A7R8CM96_LEPSM
428
0
49391
TrEMBL
other Location (Reliability: 2)
A0A817FD95_LEPSM
222
0
25548
TrEMBL
other Location (Reliability: 3)
A0A7R8D3J3_LEPSM
530
0
61108
TrEMBL
other Location (Reliability: 1)
A0A7R8D199_LEPSM
186
0
21232
TrEMBL
other Location (Reliability: 1)
A0A7R8CD55_LEPSM
502
0
57454
TrEMBL
other Location (Reliability: 1)
A0A812E5R2_SEPPH
1364
0
152129
TrEMBL
other Location (Reliability: 3)
A0A7R8D5L5_LEPSM
397
0
46941
TrEMBL
other Location (Reliability: 2)
A0A817FE71_LEPSM
338
0
39056
TrEMBL
other Location (Reliability: 5)
A0A7R8CYX1_LEPSM
932
0
103799
TrEMBL
other Location (Reliability: 2)
Q96028_9AVES
340
0
37840
TrEMBL
-
ASH1L_MOUSE
2958
0
331333
Swiss-Prot
-
ASH1L_HUMAN
2969
0
332790
Swiss-Prot
Secretory Pathway (Reliability: 1)