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2.1.1.357: [histone H3]-lysine36 N-dimethyltransferase

This is an abbreviated version!
For detailed information about [histone H3]-lysine36 N-dimethyltransferase, go to the full flat file.

Word Map on EC 2.1.1.357

Reaction

2 S-adenosyl-L-methionine +

a [histone H3]-L-lysine36
= 2 S-adenosyl-L-homocysteine +
a [histone H3]-N6,N6-dimethyl-L-lysine36

Synonyms

Ash1L, EC 2.1.1.43, H3K36 KMTase, H3K36 methyltransferase, H3K36-specific methyltransferase, histone H3 lysine 36 methyltransferase, KMT3B, KMT3C, Metnase, MMSET, NSD1, NSD2, NSD3, nuclear receptor SET domain containing protein 2, nuclear receptor-binding SET domain protein 2, SET, SETD2, SETMAR, Smyd2, Whsc1, WHSC1L1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase

Application

Application on EC 2.1.1.357 - [histone H3]-lysine36 N-dimethyltransferase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
synthesis
expression of NSDs via tagging with a human influenza hemagglutinin tag greatly improves the quality of the recombinant NSDs, resulting in more than 95% pure, stable, and active NSD-hemagglutinins, with an increase in production yield up to 22.4fold and up to 6.25 mg/l from LB Eschewrichia coli culture, and without further purification