2.1.1.346: U6 snRNA m6A methyltransferase

This is an abbreviated version!
For detailed information about U6 snRNA m6A methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.346

2.1.1.346

mettl3

alkbh5

methyltransferases

writer

epitranscriptome

n6-adenosine

ythdf3

erasers

igf2bp1

demethylases

malat1

rbm15b

Reaction

Synonyms

m6A methyltransferase, m6A RNA methyltransferase, methyltransferase like protein 16, methyltransferase-like protein 16, METTL16, N6-methyladenosine (m6A) methyltransferase, RNA m6A methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.346 U6 snRNA m6A methyltransferase

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Results	in table
423	AA Sequence
2	Cloned(Commentary)
2	Crystallization (Commentary)
95	Disease/ Diagnostics
6	General Information
3	Localization
11	Natural Substrates/ Products (Substrates)
9	Organism
9	PDB ID
1	Purification (Commentary)
1	Reaction
9	Reference
5	Source Tissue
16	Substrates and Products (Substrate)
3	Subunits
17	Synonyms
1	Systematic Name

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Reference on EC 2.1.1.346 - U6 snRNA m6A methyltransferase

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744644

Pendleton, K.E.; Chen, B.; Liu, K.; Hunter, O.V.; Xie, Y.; Tu, B.P.; Conrad, N.K.

The U6 snRNA m6A methyltransferase METTL16 regulates SAM synthetase intron retention

Cell

169

824-835.e14

2017

Homo sapiens (Q86W50), Homo sapiens

28525753

744790

Warda, A.S.; Kretschmer, J.; Hackert, P.; Lenz, C.; Urlaub, H.; Hoebartner, C.; Sloan, K.E.; Bohnsack, M.T.

Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs

EMBO Rep.

2004-2014

2017

Homo sapiens (Q86W50), Homo sapiens

29051200

745910

Shimba, S.; Bokar, J.A.; Rottman, F.; Reddy, R.

Accurate and efficient N-6-adenosine methylation in spliceosomal U6 small nuclear RNA by HeLa cell extract in vitro

Nucleic Acids Res.

2421-2426

1995

Homo sapiens (Q86W50)

7630720

745965

Yeon, S.Y.; Jo, Y.S.; Choi, E.J.; Kim, M.S.; Yoo, N.J.; Lee, S.H.

Frameshift mutations in repeat sequences of ANK3, HACD4, TCP10L, TP53BP1, MFN1, LCMT2, RNMT, TRMT6, METTL8 and METTL16 genes in colon cancers

Pathol. Oncol. Res.

617-622

2018

Homo sapiens (Q86W50)

28803425

757652

Mendel, M.; Chen, K.M.; Homolka, D.; Gos, P.; Pandey, R.R.; McCarthy, A.A.; Pillai, R.S.

Methylation of structured RNA by the m6A writer METTL16 is essential for mouse embryonic development

Mol. Cell

986-1000

2018

Homo sapiens (Q86W50), Homo sapiens, Mus musculus (Q9CQG2), Mus musculus

30197299

757751

Koh, C.w.Q.; Goh, Y.T.; Goh, W.S.S.

Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes

Nat. Commun.

5636

2019

Homo sapiens (Q86W50)

31822664

758186

Nance, D.J.; Satterwhite, E.R.; Bhaskar, B.; Misra, S.; Carraway, K.R.; Mansfield, K.D.

Characterization of METTL16 as a cytoplasmic RNA binding protein

PLoS One

e0227647

2020

Homo sapiens (Q86W50)

31940410

758436

Ruszkowska, A.; Ruszkowski, M.; Dauter, Z.; Brown, J.A.

Structural insights into the RNA methyltransferase domain of METTL16

Sci. Rep.

5311

2018

Homo sapiens (Q86W50)

29593291