1.14.99.66: [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

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For detailed information about [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase, go to the full flat file.

Word Map on EC 1.14.99.66

1.14.99.66

chromatin

demethylation

corest

corepressors

deacetylases

chromatin-modifying

tranylcypromine

lsd1-mediated

lys4

demethylase-1

di-methylated

swirm

h3k4me1

pargyline

diagnostics

drug development

Reaction

+ 2 acceptor + 2 H2O =

+ 2 formaldehyde + 2 reduced acceptor

Synonyms

amine oxidase flavin-containing domain 1, amine-oxidase flavin-containing domain 1, AOF1, AOF2, BHC110, BHC110/LSD1, CG9088, demethylase LSD1, dJARID1/Lid, H3K4 demethylase, H3K4me2 demethylase, H3K4me2/1 histone demethylase, histone demethylase, histone H3 K4 demethylase, histone H3 lysine 4 demethylase, histone H3K4 demethylase, histone lysine-specific demethylase 1, Jarid1, KDM1, KDM1A, KDM1B, KIAA0601, LD40310, Lid, LSD1, LSD1 demethylase, LSD1/KDM1, LSD1/KDM1A, LSD2, lysine demethylase 1B, lysine specific demethylase 1, lysine-specific demethylase 1, lysine-specific demethylase 1A, lysine-specific demethylase 2, lysine-specific demethylase-1, lysine-specific histone demethylase, lysine-specific histone demethylase 1, lysine-specific histone demethylase 1A, lysine-specific histone demethylase 1B, lysinespecific demethylase 1, More, SPR-5

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.99 Miscellaneous

1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

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Results	in table
6	Activating Compound
9	AA Sequence
3	Application
20	Cloned(Commentary)
32	Cofactor
11	Crystallization (Commentary)
292	Disease/ Diagnostics
2	Expression
86	General Information
9	IC50 Value
139	Inhibitors
7	kcat/KM [mM/s]
26	Ki Value [mM]
23	KM Value [mM]
47	Localization
3	Metals/Ions
3	Molecular Weight [Da]
97	Natural Substrates/ Products (Substrates)
123	Organism
20	PDB ID
9	pH Optimum
1	pH Range
1	Posttranslational Modification
21	Protein Variants
10	Purification (Commentary)
3	Reaction
64	Reference
86	Source Tissue
155	Substrates and Products (Substrate)
5	Subunits
161	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
18	Turnover Number [1/s]

Organism

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Organism on EC 1.14.99.66 - [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase

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Arabidopsis thaliana

2 entries

Caenorhabditis elegans

3 entries

Drosophila melanogaster

Mus musculus C57/BL6J

725541

Mus musculus C57BL/6

male apolipoprotein knockout (apoE KO) mice

753388

Q6ZQ88

UniProt

Mus musculus C57BL/6J

753349

Q6ZQ88

UniProt