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1.14.14.73: albendazole monooxygenase (sulfoxide-forming)

This is an abbreviated version!
For detailed information about albendazole monooxygenase (sulfoxide-forming), go to the full flat file.

Word Map on EC 1.14.14.73

Reaction

albendazole
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
albendazole S-oxide
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

albendazole hydroxylase, albendazole sulfoxidase, BVMORj24, CYP1A2, CYP2J2, CYP3A4, cytochrome P450 2J2, MT1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.73 albendazole monooxygenase (sulfoxide-forming)

Natural Substrates Products

Natural Substrates Products on EC 1.14.14.73 - albendazole monooxygenase (sulfoxide-forming)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
albendazole + [reduced NADPH-hemoprotein reductase] + O2
albendazole S-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
fenbendazole + [reduced NADPH-hemoprotein reductase] + O2
fenbendazole S-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?