Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.14.73: albendazole monooxygenase (sulfoxide-forming)

This is an abbreviated version!
For detailed information about albendazole monooxygenase (sulfoxide-forming), go to the full flat file.

Word Map on EC 1.14.14.73

Reaction

albendazole
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
albendazole S-oxide
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

albendazole hydroxylase, albendazole sulfoxidase, BVMORj24, CYP1A2, CYP2J2, CYP3A4, cytochrome P450 2J2, MT1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.73 albendazole monooxygenase (sulfoxide-forming)

General Information

General Information on EC 1.14.14.73 - albendazole monooxygenase (sulfoxide-forming)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
-
metabolism of albendazole to albendazole-sulfoxide by pig liver microsomes is dependent on both microsomal cytochrome P-450 and FAD-containing mono-oxygenase enzymes. the relative contributions of the two systems depend on the concentration of albendazole
physiological function