1.14.14.145: abieta-7,13-dien-18-ol hydroxylase

This is an abbreviated version!
For detailed information about abieta-7,13-dien-18-ol hydroxylase, go to the full flat file.

abieta-7,13-dien-18-ol hydroxylase, abietadienol/abietadienal oxidase, CYP720B1, CyPA, CYPA1, CYPA2, CyPB, CYPC, CYPD, EC 1.14.13.109, PtAO

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Results	in table
1	Activating Compound
78	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
5	Cofactor
5	IC50 Value
6	Inhibitors
16	KM Value [mM]
5	Localization
8	Natural Substrates/ Products (Substrates)
12	Organism
3	Pathway
4	pH Optimum
2	pH Range
4	Reaction
11	Reference
5	Source Tissue
1	Specific Activity [micromol/min/mg]
24	Substrates and Products (Substrate)
19	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Reaction on EC 1.14.14.145 - abieta-7,13-dien-18-ol hydroxylase

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abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O

(1b), spontaneous

abieta-7,13-dien-18-al + [reduced NADPH-hemoprotein reductase] + O2 = abieta-7,13-dien-18-oate + [oxidized NADPH-hemoprotein reductase] + H2O

(1c)

abieta-7,13-dien-18-ol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = abieta-7,13-dien-18-oate + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O

overall reaction

abieta-7,13-dien-18-ol + [reduced NADPH-hemoprotein reductase] + O2 = abieta-7,13-dien-18,18-diol + [oxidized NADPH-hemoprotein reductase] + H2O

(1a)