1.14.14.145: abieta-7,13-dien-18-ol hydroxylase

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For detailed information about abieta-7,13-dien-18-ol hydroxylase, go to the full flat file.

Reaction

Synonyms

abieta-7,13-dien-18-ol hydroxylase, abietadienol/abietadienal oxidase, CYP720B1, CyPA, CYPA1, CYPA2, CyPB, CYPC, CYPD, EC 1.14.13.109, PtAO

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.145 abieta-7,13-dien-18-ol hydroxylase

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Results	in table
1	Activating Compound
78	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
5	Cofactor
5	IC50 Value
6	Inhibitors
16	KM Value [mM]
5	Localization
8	Natural Substrates/ Products (Substrates)
12	Organism
3	Pathway
4	pH Optimum
2	pH Range
4	Reaction
11	Reference
5	Source Tissue
1	Specific Activity [micromol/min/mg]
24	Substrates and Products (Substrate)
19	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

IC50 Value

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IC50 Value on EC 1.14.14.145 - abieta-7,13-dien-18-ol hydroxylase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0013

clotrimazole

Abies grandis

-

pH 7.5, 32°C

690605

0.004

cytochrome c

Abies grandis

-

pH 7.5, 32°C

690605

0.005

Metyrapone

Abies grandis

-

pH 7.5, 32°C

690605

0.307

miconazole

Abies grandis

-

pH 7.5, 32°C

690605

additional information

additional information

Abies grandis

-

no inhibition detected by ancymidol at 0.2 mM

690605

-