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2.1.1.148: thymidylate synthase (FAD)

This is an abbreviated version!
For detailed information about thymidylate synthase (FAD), go to the full flat file.

Word Map on EC 2.1.1.148

Reaction

5,10-methylenetetrahydrofolate
+
dUMP
 +
NADPH
 +
H+
=
dTMP
 +
tetrahydrofolate
 +
NADP+

Synonyms

A674R, complementing thymidylate synthase, FDTS, flavin dependent thymidylate synthase, flavin-dependent thymidylate synthase, flavin-dependent thymidylate synthase X, flavin-dependent TS, Thy1, thymidylate synthase 1, thymidylate synthase complementing protein, thymidylate synthase ThyX, thymidylate synthase X, ThyX, thyX-encoded thymidylate synthase, TSCP, TTHA1096

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.148 thymidylate synthase (FAD)

Temperature Stability

Temperature Stability on EC 2.1.1.148 - thymidylate synthase (FAD)

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100.4
melting temperature, mutant S88W
102.4
melting temperature, wild-type
103.1
melting temperature, mutant Y91F
107.2
melting temperature, mutant S88W, presence of FAD
107.3
melting temperature, wild-type, presence of FAD
107.4
melting temperature, mutant Y91F, presence of FAD