2.3.1.9: acetyl-CoA C-acetyltransferase
This is an abbreviated version!
For detailed information about acetyl-CoA C-acetyltransferase, go to the full flat file.
Word Map on EC 2.3.1.9
-
2.3.1.9
-
ketone
-
mevalonate
-
hmg-coa
-
acetoacetate
-
beta-oxidation
-
3-hydroxy-3-methylglutaryl-coa
-
beta-ketothiolase
-
2-methyl-3-hydroxybutyrate
-
3-hydroxybutyrate
-
acetoacetyl-coenzyme
-
ketoacidotic
-
ketogenesis
-
tiglylglycine
-
aacts
-
coa-transferase
-
2-methylacetoacetate
-
thiolytic
-
3-oxoacyl-coas
-
3-ketothiolase
-
3-hydroxyacyl-coa
-
coash
-
3-hydroxybutyryl-coa
-
lyso-paf
-
ketone-body
-
synthesis
-
analysis
-
biofuel production
- 2.3.1.9
- ketone
- mevalonate
- hmg-coa
- acetoacetate
-
beta-oxidation
- 3-hydroxy-3-methylglutaryl-coa
- beta-ketothiolase
- 2-methyl-3-hydroxybutyrate
- 3-hydroxybutyrate
-
acetoacetyl-coenzyme
-
ketoacidotic
-
ketogenesis
-
tiglylglycine
-
aacts
-
coa-transferase
- 2-methylacetoacetate
-
thiolytic
- 3-oxoacyl-coas
- 3-ketothiolase
- 3-hydroxyacyl-coa
- coash
- 3-hydroxybutyryl-coa
-
lyso-paf
-
ketone-body
- synthesis
- analysis
- biofuel production
Reaction
2 acetyl-CoA
=
Synonyms
2-methylacetoacetyl-CoA thiolase, 3-ketoacyl-CoA (T1)-like thiolase, 3-ketoacyl-CoA thiolase, 3-ketoacyl-coenzyme A thiolase, 3-oxothiolase, A1887, AACT, AACT1, AACT2, ACAT, ACAT1, ACAT2, ACCT, acetoacetyl CoA thiolase, acetoacetyl-CoA acetyltransferase, acetoacetyl-CoA C-acetyltransferase, acetoacetyl-CoA thiolase, acetoacetyl-CoA thiolase T2, acetyl coenzyme A thiolase, acetyl-CoA acetyltransferase, acetyl-CoA C-acetyltransferase, acetyl-CoA:N-acetyltransferase, acetyltransferase, acetyl coenzyme A, ACOAT, ACTRANS, AFUB_000550, AtoB, beta-acetoacetyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketothiolase, CT, cytosolic acetoacetyl-CoA thiolase, cytosolic acetoacetyl-CoA thiolase 1, cytosolic acetoacetyl-CoA thiolase 2, ERG10, Erg10A, HFX_1022, HFX_1023, HFX_6003, HFX_6004, KACT, MmgA, Msed_0656, MSM-13 thiolase, OsAT1, phaA, ReH16_B0759, thiolase II, ThL, Tneu_0249, type II thiolase
ECTree
2.3.1.9 acetyl-CoA C-acetyltransferaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 2.3.1.9 - acetyl-CoA C-acetyltransferase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2 acetyl-CoA
acetoacetyl-CoA + CoA
the thiolase is involved in the synthesis and catabolism of fatty acids
-
-
?
2-methylacetoacetyl-CoA + CoA
acetyl-CoA + propionyl-CoA
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cleavage of 2-methylacetoacetyl-CoA in the isoleucine catabolism
-
-
?
acetoacetyl-CoA + CoA
2 acetyl-CoA
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interconversion of 2 acetyl-CoA into acetoacetyl-CoA in the ketone body metabolism
-
-
r
2 acetyl-CoA
CoA + acetoacetyl-CoA
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
-
-
-
r
2 acetyl-CoA
CoA + acetoacetyl-CoA
the enzyme is responsible for supplying the precursors for biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
-
-
?
2 acetyl-CoA
CoA + acetoacetyl-CoA
the enzyme is responsible for supplying the precursors for biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
-
-
?
2 acetyl-CoA
CoA + acetoacetyl-CoA
the enzyme catalyzes a reaction in the mevalonate pathway
-
-
?
2 acetyl-CoA
CoA + acetoacetyl-CoA
the enzyme catalyzes a reaction in the mevalonate pathway
-
-
?
acetyl-CoA + acetyl-CoA
CoA + acetoacetyl-CoA
-
enzyme deficiency affects isoleucine and ketone body metabolism
-
-
r
acetyl-CoA + acetyl-CoA
CoA + acetoacetyl-CoA
involved in fatty acid synthesis
-
-
r
CoA + acetoacetyl-CoA
2 acetyl-CoA
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
-
-
-
?
CoA + acetoacetyl-CoA
2 acetyl-CoA
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
-
-
-
r
CoA + acetoacetyl-CoA
2 acetyl-CoA
the enzyme is involved in the 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway
-
-
?
CoA + acetoacetyl-CoA
2 acetyl-CoA
the enzyme is involved in the 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway
-
-
?
CoA + acetoacetyl-CoA
2 acetyl-CoA
the enzyme is involved in autotrophic carbon fixation
-
-
?
CoA + acetoacetyl-CoA
2 acetyl-CoA
the enzyme is involved in autotrophic carbon fixation
-
-
?
CoA + acetoacetyl-CoA
2 acetyl-CoA
-
the enzyme of the biosynthetic pathway for polyhydroxyalkanoates
-
-
r
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
cytosolic thiolase I is essential for the mevalonate pathway
-
?
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
-
enzyme of fatty acid oxidation cycle
-
?
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
-
peroxisomal thiolase most probably catalyzes the first reaction in peroxisomal cholesterol and dolichol synthesis
-
?
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
-
liver mitochondrial isoenzyme catalyzes the first step in biosynthesis of ketone bodies
-
?
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
-
involved in generation of acetoacetyl-CoA for poly-beta-hydroxybutyrate synthesis
-
?
additional information
?
-
the enzyme shows degradative thiolase activity by converting 3-ketoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
-
the enzyme shows degradative thiolase activity by converting 3-ketoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
the enzyme shows degradative thiolase activity by converting 3-ketoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
the enzyme shows degradative thiolase activity by converting 3-oxoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
the enzyme shows degradative thiolase activity by converting 3-ketoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
the enzyme shows degradative thiolase activity by converting 3-ketoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
Cupriavidus necator H16 / ATCC 23440 / NCIB 10442 / S-10-1
the enzyme shows degradative thiolase activity by converting 3-oxoacyl-CoA to acyl-CoA
-
-
?
additional information
?
-
-
no activity is observed with acetyl-CoA
-
-
?
additional information
?
-
-
the enzyme plays a more important role in the activation of ketogenesis in Squalus acanthias than in mammals and birds
-
-
?
