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1.21.4.5: tetrachlorohydroquinone reductive dehalogenase

This is an abbreviated version!
For detailed information about tetrachlorohydroquinone reductive dehalogenase, go to the full flat file.

Word Map on EC 1.21.4.5

Reaction

2,3,6-trichlorohydroquinone
+
Cl-
 +
glutathione disulfide
=
2,3,5,6-tetrachlorohydroquinone
 + 2 glutathione

Synonyms

PCP hydroxylase, pcpC, TCHQ dehalogenase, tetrachloro-p-hydroquinone reductive dehalogenase, tetrachlorohydroquinone dehalogenase, tetrachlorohydroquinone reductive dehalogenase

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.4 With a disulfide as acceptor
                1.21.4.5 tetrachlorohydroquinone reductive dehalogenase

Reference

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Reference on EC 1.21.4.5 - tetrachlorohydroquinone reductive dehalogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Habash, M.B.; Beaudette, L.A.; Cassidy, M.B.; Leung, K.T.; Hoang, T.A.; Vogel, H.J.; Trevors, J.T.; Lee, H.
Characterization of tetrachlorohydroquinone reductive dehalogenase from Sphingomonas sp. UG30
Biochem. Biophys. Res. Commun.
299
634-640
2002
Sphingobium sp. UG30 (Q937X0)
Manually annotated by BRENDA team
McCarthy, D.L.; Navarrete, S.; Willett, W.S.; Babbitt, P.C.; Copley, S.D.
Exploration of the relationship between tetrachlorohydroquinone dehalogenase and the glutathione S-transferase superfamily
Biochemistry
35
14634-14642
1996
Sphingobium chlorophenolicum (Q03520), Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Kiefer, P.M.; McCarthy, D.L.; Copley, S.D.
The reaction catalyzed by tetrachlorohydroquinone dehalogenase does not involve nucleophilic aromatic substitution
Biochemistry
41
1308-1314
2002
Sphingobium chlorophenolicum (Q03520), Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Kiefer, P.M.; Copley, S.D.
Characterization of the initial steps in the reductive dehalogenation catalyzed by tetrachlorohydroquinone dehalogenase
Biochemistry
41
1315-1322
2002
Sphingobium chlorophenolicum (Q03520)
Manually annotated by BRENDA team
Warner, J.R.; Lawson, S.L.; Copley, S.D.
A mechanistic investigation of the thiol-disulfide exchange step in the reductive dehalogenation catalyzed by tetrachlorohydroquinone dehalogenase
Biochemistry
44
10360-10368
2005
Sphingobium chlorophenolicum (Q03520), Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Warner, J.R.; Copley, S.D.
Pre-steady-state kinetic studies of the reductive dehalogenation catalyzed by tetrachlorohydroquinone dehalogenase
Biochemistry
46
13211-13222
2007
Sphingobium chlorophenolicum (Q03520), Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Warner, J.R.; Copley, S.D.
Mechanism of the severe inhibition of tetrachlorohydroquinone dehalogenase by its aromatic substrates
Biochemistry
46
4438-4447
2007
Sphingobium chlorophenolicum (Q03520), Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Willett, W.S.; Copley, S.D.
Identification and localization of a stable sulfenic acid in peroxide-treated tetrachlorohydroquinone dehalogenase using electrospray mass spectrometry
Chem. Biol.
3
851-857
1996
Sphingobium chlorophenolicum (Q03520)
Manually annotated by BRENDA team
Xun, L.; Topp, E.; Orser, C.
Purification and characterization of a tetrachloro-p-hydroquinone reductive dehalogenase from a Flavobacterium sp
J. Bacteriol.
174
8003-8007
1992
Sphingobium chlorophenolicum (Q03520)
Manually annotated by BRENDA team
Habash, M.; Chu, B.C.; Trevors, J.T.; Lee, H.
Mutational study of the role of N-terminal amino acid residues in tetrachlorohydroquinone reductive dehalogenase from Sphingomonas sp. UG30
Res. Microbiol.
160
553-559
2009
Sphingobium sp. UG30 (Q937X0)
Manually annotated by BRENDA team