Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.20.B3: cycloclavine dioxygenase (alternatively: multifunctional dioxygenase EasH)

This is an abbreviated version!
For detailed information about cycloclavine dioxygenase (alternatively: multifunctional dioxygenase EasH), go to the full flat file.

Reaction

an ergot alkaloid
+
O2
+
2-oxoglutarate
=
a cyclopropyl-ergot alkaloid
+
succinate
+
CO2
+
H2O

Synonyms

EasH

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
                1.14.20.B3 cycloclavine dioxygenase (alternatively: multifunctional dioxygenase EasH)

Substrates Products

Substrates Products on EC 1.14.20.B3 - cycloclavine dioxygenase (alternatively: multifunctional dioxygenase EasH)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
6,8beta-dimethyl-6,7-didehydroergolin-6-ium + O2 + 2-oxoglutarate
6,8alpha-dimethyl-10beta-6,7-didehydro-8,10-cycloergolin-6-ium + succinate + CO2 + H2O
show the reaction diagram
additional information
?
-
no substrates: festuclavine, agroclavine and chanoclavine-I aldehyde
-
-
-