1.14.19.67: salutaridine synthase

This is an abbreviated version!
For detailed information about salutaridine synthase, go to the full flat file.

Reaction

Synonyms

(R)-reticuline dehydrogenase, (R)-reticuline oxidase (C-C phenol-coupling), CYP719B1, dehydrogenase, (R)-reticuline, EC 1.1.3.35, EC 1.14.21.4, PsSAS, SalSyn, salutaridine synthase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.19 With oxidation of a pair of donors resulting in the reduction of O₂ to two molecules of water

                1.14.19.67 salutaridine synthase

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Results	in table
1	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
10	Cofactor
6	Disease/ Diagnostics
1	General Information
3	Inhibitors
4	KM Value [mM]
11	Localization
3	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
11	Organism
6	Pathway
3	pH Optimum
1	pH Range
2	Purification (Commentary)
2	Reaction
5	Reaction Type
11	Reference
11	Source Tissue
4	Storage Stability
11	Substrates and Products (Substrate)
2	Subunits
11	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.14.19.67 - salutaridine synthase

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SYSTEMATIC NAME

IUBMB Comments

(R)-reticuline,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (C-C phenol-coupling)

A cytochrome P-450 (heme-thiolate) protein found in plants. Forms the morphinan alkaloid salutaridine by intramolecular phenol oxidation of reticuline without the incorporation of oxygen into the product.