1.14.19.67: salutaridine synthase

This is an abbreviated version!
For detailed information about salutaridine synthase, go to the full flat file.

Reaction

Synonyms

(R)-reticuline dehydrogenase, (R)-reticuline oxidase (C-C phenol-coupling), CYP719B1, dehydrogenase, (R)-reticuline, EC 1.1.3.35, EC 1.14.21.4, PsSAS, SalSyn, salutaridine synthase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.19 With oxidation of a pair of donors resulting in the reduction of O₂ to two molecules of water

                1.14.19.67 salutaridine synthase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
10	Cofactor
6	Disease/ Diagnostics
1	General Information
3	Inhibitors
4	KM Value [mM]
11	Localization
3	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
11	Organism
6	Pathway
3	pH Optimum
1	pH Range
2	Purification (Commentary)
2	Reaction
5	Reaction Type
11	Reference
11	Source Tissue
4	Storage Stability
11	Substrates and Products (Substrate)
2	Subunits
11	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

Substrates Products

print visible entries

print all entries

Substrates Products on EC 1.14.19.67 - salutaridine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Substrate/Product Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(R)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2

norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

2 entries

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + 2 H2O

Papaver somniferum

B1NF18

-

743574

-

-

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

7 entries

(R/S)-orientaline + [reduced NADPH-hemoprotein reductase] + O2

?

Sus scrofa

-

-

393876

-

-

?

(R)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2

norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

B1NF18

-

698930, 720707

-

-

?

(R)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2

norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

-

-

720707

-

-

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

B1NF18

-

698930, 720707

-

-

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

-

-

720707

-

-

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

B1NF18

-

728475

-

-

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

-

strictly dependent on NADPH as reducing cofactor and on (R)-configurated reticuline

393875

-

393875

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Papaver somniferum

-

formation of salutaridine, a key intermediate in morphine biosynthesis

393875

-

393875

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Sus scrofa

-

highly regioselective and stereoselective enzyme

393876

-

393876

?

(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2

salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O

Sus scrofa

-

critical step in morphine biosynthesis

393876

-

393876

?