1.14.14.178: steroid 22S-hydroxylase
This is an abbreviated version!
For detailed information about steroid 22S-hydroxylase, go to the full flat file.
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Synonyms
AOD4, BR C-22 hydroxylase, C-22 hydroxylase, CYP724A1, CYP724B2, CYP90B1, CYP90B3, DWARF4, Dwf4, steroid 22-hydroxylase, steroid 22-monooxygenase
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General Information
General Information on EC 1.14.14.178 - steroid 22S-hydroxylase
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malfunction
metabolism
physiological function
dwf4-5D mutants display reduced sensitivity to methyl jasmonate and exhibit increased susceptibility to Pseudomonas syringae
malfunction
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enzyme null mutants show severe symptoms of brassinosteroid deficiency
the expression of DWARF4, which encodes a C-22 hydroxylase, is crucial for brassinosteroid biosynthesis and for the feedback control of endogenous brassinosteroid levels. The amount of the DWF4 mRNA precursor either decreases or increases, similarly with its mature form, in response to an exogenously applied bioactive brassinosteroid, brassinolide, and a brassinosteroid biosynthesis inhibitor, brassinazole, respectively. Brassinosteroids act positively on root elongation under the control of auxin
the expression of DWARF4, which encodes a C-22 hydroxylase, is crucial for brassinosteroid biosynthesis and for the feedback control of endogenous brassinosteroid levels. DWF4 transcription plays an important role in the brassinosteroid-auxin crosstalk associated with root elongation, in addition to its role in brassinosteroid homeostasis
physiological function
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enzyme over-expression in wild type Arabidopsis enhances the height of inflorescence stems, number of branches and productivity of seeds
physiological function
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the enzyme plays a positive role in improving growth rate and elevating biomass production in poplar. Enzyme overexpression in poplar promotes growth rate and biomass yield, increases area and cell layers of xylem. Transgenic plants show a significant increase in plant height and stem diameter compared with the wild type
physiological function
the enzyme plays a role in regulation of plant growth and development
physiological function
the enzyme plays an important role in potato plant respone to salt stress. The overexpressing of enzyme in potato plantlets can enhance the salt resistance by alleviating the negative effects of salt-stress
physiological function
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transgenic Brassica napus plants, in comparison to wild type, display increased seed yield leading to increased overall oil content per plant, higher root biomass and root length, significantly better tolerance to dehydration and heat stress, and enhanced resistance to necrotrophic fungal pathogens Leptosphaeria maculans and Sclerotinia sclerotiorum