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1.14.14.178: steroid 22S-hydroxylase

This is an abbreviated version!
For detailed information about steroid 22S-hydroxylase, go to the full flat file.

Reaction

a C27-steroid
+
O2
+
=
a (22S)-22-hydroxy-C27-steroid
+ 2 H2O +

Synonyms

AOD4, BR C-22 hydroxylase, C-22 hydroxylase, CYP724A1, CYP724B2, CYP90B1, CYP90B3, DWARF4, Dwf4, steroid 22-hydroxylase, steroid 22-monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.178 steroid 22S-hydroxylase

Expression

Expression on EC 1.14.14.178 - steroid 22S-hydroxylase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
auxin stimulates the expression of the enzyme gene
downregulation of enzyme expression by brassinosteroid biosynthesis inhibitor brassinazole
during seed germination, the enzyme is mainly expressed in the embryo roots and its expression level increases linearly with the length of embryo roots from the apex
-
enzyme expression level is positively regulated by the transcription factor TCP1
jasmonate represses the expression of the enzyme gene
no significant expression change is observed after the treatment with abscisic acid, 1-aminocyclopropane-1-carboxylic acid, gibberellin, jasmonic acid, indole-3-acetic acid, and cytokinin
-
overexpression of TCP1 directly upregulates the expression of the enzyme
-
the enzyme is downregulated almost 10times in 3 h after brassinolide treatment
-
upreguation by bioactive brassinosteroid, brassinolide
white light and monochromatic blue LED light perception in above ground tissues triggers enzyme accumulation in root tips
-