1.14.14.141: psoralen synthase

This is an abbreviated version!
For detailed information about psoralen synthase, go to the full flat file.

Word Map on EC 1.14.14.141

1.14.14.141

furanocoumarins

psoralens

majus

angelicin

umbelliferone

elicitors

monooxygenase

columbianetin

angular

carthami

glycinea

p-coumaroyl

megasperma

syn-elimination

phytophthora

acetone

elicitor-induced

alternaria

Reaction

+ 2 H2O

Synonyms

CYP71AJ1, CYP71AJ2, CYP71AJ3, EC 1.14.13.102, psoralen synthase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.141 psoralen synthase

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Results	in table
4	Activating Compound
20	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
3	Cofactor
1	Expression
18	Inhibitors
7	KM Value [mM]
6	Localization
2	Metals/Ions
1	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
7	Organism
1	Pathway
4	pH Optimum
1	pI Value
1	Protein Variants
3	Purification (Commentary)
3	Reaction
7	Reference
12	Source Tissue
18	Substrates and Products (Substrate)
2	Subunits
6	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.14.14.141 - psoralen synthase

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(+)-marmesin,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase

This microsomal cytochrome P-450 (heme-thiolate) enzyme is rather specific for (+)-marmesin, although it can also accept 5-hydroxymarmesin to a much lesser extent. Furanocoumarins protect plants from fungal invasion and herbivore attack. (+)-Columbianetin, the angular furanocoumarin analogue of the linear furanocoumarin (+)-marmesin, acts as a competitive inhibitor even though it is not a substrate.