1.14.14.141: psoralen synthase
This is an abbreviated version!
For detailed information about psoralen synthase, go to the full flat file.
Word Map on EC 1.14.14.141
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1.14.14.141
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furanocoumarins
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psoralens
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majus
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angelicin
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umbelliferone
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elicitors
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monooxygenase
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columbianetin
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angular
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carthami
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glycinea
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p-coumaroyl
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megasperma
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syn-elimination
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phytophthora
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acetone
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elicitor-induced
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alternaria
- 1.14.14.141
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furanocoumarins
- psoralens
- majus
- angelicin
- umbelliferone
- elicitors
- monooxygenase
-
columbianetin
-
angular
- carthami
-
glycinea
-
p-coumaroyl
- megasperma
-
syn-elimination
-
phytophthora
- acetone
-
elicitor-induced
-
alternaria
Reaction
Synonyms
CYP71AJ1, CYP71AJ2, CYP71AJ3, EC 1.14.13.102, psoralen synthase
ECTree
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Inhibitors
Inhibitors on EC 1.14.14.141 - psoralen synthase
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(+)-columbianetin
i.e. (+)-3,4,2',3'-D4-columbianetin, competitive inhibition, binds to the active site, analogy modeling and docking analysis, mechanism-based inactivation
Ancymidole
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48% inhibition of the psoralen synthase at 0.05 mM, 29% at 0.005 mM
BAS 110
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34% inhibition of the psoralen synthase at 0.001 mM, 30% at 0.0002 mM
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complete inhibition of the psoralen synthase at 0.001 mM, 86% at 0.0002 mM
BAS 111
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52% inhibition of the psoralen synthase at 0.001 mM, 33% at 0.0002 mM
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complete inhibition of the psoralen synthase at 0.05 mM, 68% at 0.005 mM
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complete inhibition of the psoralen synthase at 0.001 mM, 74% at 0.0002 mM
ketoconazole
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38% inhibition of the psoralen synthase at 0.050 mM, 20% at 0.005 mM
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85% inhibition of the psoralen synthase at 0.001 mM, 25% at 0.0002 mM
Tetcyclacis
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47% inhibition of the psoralen synthase at 0.05 mM, 51% at 0.005 mM
no inhibition by 5- and 8-methoxypsoralen, and angelicin
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additional information
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no inhibition by 5- and 8-methoxypsoralen, and angelicin
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additional information
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no effect on enzyme activity by 2-mercaptoethanol and DTT
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