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1.14.14.141: psoralen synthase

This is an abbreviated version!
For detailed information about psoralen synthase, go to the full flat file.

Word Map on EC 1.14.14.141

Reaction

(+)-marmesin
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
psoralen
+
[oxidized NADPH-hemoprotein reductase]
+
acetone
+ 2 H2O

Synonyms

CYP71AJ1, CYP71AJ2, CYP71AJ3, EC 1.14.13.102, psoralen synthase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.141 psoralen synthase

Inhibitors

Inhibitors on EC 1.14.14.141 - psoralen synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(+)-columbianetin
i.e. (+)-3,4,2',3'-D4-columbianetin, competitive inhibition, binds to the active site, analogy modeling and docking analysis, mechanism-based inactivation
Ancymidole
BAS 110
BAS 111
BAS 978
-
carbon monoxide
-
-
cytochrome c
-
72% inhibition at 0.5 nM
ketoconazole
NADP+
-
43% product inhibition at 1 mM
Tetcyclacis
additional information
-