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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 2.3.1.309K252A acetylation of K252A mutants is reduced to approximately 30% of that of the wild type enzyme. In approximately 50% of the transfected cells, this mutant is detected on seemingly normal microtubules. In the rest of the cells, the microtubule cytoskeleton becomes disorganized and/or disintegrated 765372
Display the reaction diagram Show all sequences 2.3.1.309K252Q beta-tubulin is indistinguishable from that expressed in the wild-type control 765372
Display the reaction diagram Show all sequences 2.3.1.309K324R the K324R mutation does not significantly reduce the level of acetylation. beta-Tubulin is indistinguishable from that expressed in the wild-type control 765372
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