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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.3.1.309malfunction depleting up to 80% of San from HeLa cells significantly increases the rate of microtubule regrowth after microtubule catastrophe, although no gross defect in microtubule cytoskeleton is observed 765372
Display the reaction diagram Show all sequences 2.3.1.309physiological function Naa50/San is required during tissue proliferation for the correct interaction between the cohesin subunits Scc1 and Smc3. Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion 765800
Display the reaction diagram Show all sequences 2.3.1.309physiological function the enzyme acetylates L-lysine at position 252 of beta-tubulin, which is located at the interface of alpha/beta-tubulin heterodimers and interacts with the phosphate group of the alpha-tubulin-bound GTP. The acetylation is thought to attenuate tubulin incorporation into microtubules 765372
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