2.4.1.224: glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
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For detailed information about glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, go to the full flat file.
Word Map on EC 2.4.1.224
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2.4.1.224
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proteoglycans
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exostoses
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osteochondroma
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glycosaminoglycans
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glycosyltransferase
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hedgehog
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hspgs
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chondrosarcoma
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cartilaginous
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syndecan-1
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glypicans
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cartilage-capped
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wingless
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perlecan
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metaphyses
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decapentaplegic
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co-polymerase
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medicine
- 2.4.1.224
- proteoglycans
- exostoses
- osteochondroma
- glycosaminoglycans
- glycosyltransferase
-
hedgehog
-
hspgs
-
chondrosarcoma
-
cartilaginous
- syndecan-1
-
glypicans
-
cartilage-capped
-
wingless
- perlecan
-
metaphyses
-
decapentaplegic
-
co-polymerase
- medicine
Reaction
Synonyms
alpha-N-acetylglucosaminyltransferase II, exostosin-1, exostosin-2, Exostosin1, Exostosin2, EXT1, EXT2, extosin, glucuronyl-N-acetylglucosaminoproteoglycan 4-alpha-N-acetylglucosaminyltransferase, heparan sulfate polymerase, heparan sulfate synthesis enzyme, KfiA, More, N-acetyl-D-glucosaminyl-(N-acetyl-D-glucosamine) transferase, sister of tout velu, sister of tout-velu, sotv, tout-velu, ttv, UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase
ECTree
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Source Tissue
Source Tissue on EC 2.4.1.224 - glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
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the mRNA expression of EXT2, one of the crucial enzymes for heparan sulfate-glycosaminoglycan synthesis, is markedly up-regulated in injured hypoglossal motor neurons after axotomy
EXT1, NDST1, and NDST2 differentially regulate heparan sulfate biosynthesis in human tooth germ
additional information
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zebrafish ext2 gene is ubiquitously expressed during zebrafish development
loss of one copy of either the EXT1 or EXT2 gene product compromises the perichondrial chondrocytes ability to differentiate normally and to survive in a differentiated state in vitro
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FBJ, highly metastatic mouse osteosarcoma FBJ-LL cells and the poorly metastatic FBJ-S1 cells are produced from a FBJ virus-induced osteosarcoma
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FBJ, highly metastatic mouse osteosarcoma FBJ-LL cells and the poorly metastatic FBJ-S1 cells are produced from a FBJ virus-induced osteosarcoma
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