2.4.1.142: chitobiosyldiphosphodolichol beta-mannosyltransferase

This is an abbreviated version!
For detailed information about chitobiosyldiphosphodolichol beta-mannosyltransferase, go to the full flat file.

Reaction

Synonyms

ALG1, ALG1 beta1,4 mannosyltransferase, Alg1 mannosyltransferase, Alg1 protein, Alg1p, beta-1,4 mannosyltransferase, beta1,4-MT, chitobiosyldiphosphodolichol beta-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase, guanosine diphosphate-mannose:GlcNAc2-PP-dolichol mannosyltransferase-1, guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase, mannosyltransferase I, MT-1, MT-I

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.142 chitobiosyldiphosphodolichol beta-mannosyltransferase

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Results	in table
7	Activating Compound
1336	AA Sequence
1	Application
1	CAS Registry Number
8	Cloned(Commentary)
9	Disease/ Diagnostics
1	Expression
7	General Information
9	Inhibitors
2	KM Value [mM]
9	Localization
4	Metals/Ions
11	Natural Substrates/ Products (Substrates)
17	Organism
6	Pathway
4	pH Optimum
26	Protein Variants
3	Purification (Commentary)
1	Reaction
1	Reaction Type
15	Reference
15	Source Tissue
2	Specific Activity [micromol/min/mg]
2	Storage Stability
19	Substrates and Products (Substrate)
1	Subunits
23	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Disease

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Disease on EC 2.4.1.142 - chitobiosyldiphosphodolichol beta-mannosyltransferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Congenital disorder of glycosylation type Ik (CDG-Ik): a defect of mannosyltransferase I.

14973782

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik.

14973778

Pemphigoid, Bullous

A successful treatment with ustekunumab in a case of anti-laminin-?1 pemphigoid associated with psoriasis.

23252972

Psoriasis

A successful treatment with ustekunumab in a case of anti-laminin-?1 pemphigoid associated with psoriasis.

23252972

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