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2.3.1.286: protein acetyllysine N-acetyltransferase

This is an abbreviated version!
For detailed information about protein acetyllysine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.286

Reaction

[protein]-N6-acetyl-L-lysine
+
NAD+
 +
H2O
=
[protein]-L-lysine
 +
2''-O-acetyl-ADP-D-ribose
 +
nicotinamide

Synonyms

Af2Sir2, Clr3, CobB, HDAC, histone deacetylase, Hst1, HST2, Hst2p, KAT, More, NAD+-dependent protein deacetylase, NAD-dependent histone deacetylase, NAD-dependent protein deacetylase, nicotinamide adenine dinucleotide-dependent protein deacetylase, patZ, peptidyl-lysine N-acetyltransferase, phnO, protein lysine acetyltransferase, protein lysine deacetylase, Rv1151c, silent information regulator 2, Sir-2, Sir2, SIR2-Af1, Sir2-Af2, Sir2A, Sir2Af2, Sir2alpha, Sir2p, SIRT1, SIRT2, SIRT3, SIRT5, sirtuin, sirtuin 1, sirtuin 3, sirtuin-2 deacetylase, YfiQ, YiaC, YjaB

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.286 protein acetyllysine N-acetyltransferase

KCat KM Value

KCat KM Value on EC 2.3.1.286 - protein acetyllysine N-acetyltransferase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.15 - 2.2
KSTGGAcKAPRKQ
0.026 - 14.5
[histone H3]-N6-acetyl-L-lysine9
0.16
[histone H3]-N6-butyryl-L-lysine9
at pH 8.0 and 37°C
10 - 74
[histone H3]-N6-myristoyl-L-lysine9
0.92
[histone H3]-N6-octanoyl-L-lysine9
at pH 8.0 and 37°C