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2.3.1.23: 1-acylglycerophosphocholine O-acyltransferase

This is an abbreviated version!
For detailed information about 1-acylglycerophosphocholine O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.23

Reaction

acyl-CoA
+
1-acyl-sn-glycero-3-phosphocholine
=
CoA
 +
1,2-diacyl-sn-glycero-3-phosphocholine

Synonyms

1-acyl-sn-glycero-3-phosphocholine acyltransferase, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-acylglycerophosphocholine acyltransferase, 1-AGP acyltransferase 8, 1-AGPAT 8, 1-AGPAT7, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acyl coenzyme A-monoacylphosphatidylcholine acyltransferase, acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase, acyl-CoA:glycerophosphocholine acyltransferase, acyl-CoA:lysocardiolipin acyltransferase 1, acyl-CoA:lysophosphatidylcholine acyltransferase, acyl-CoA:lysophosphatidylethanolamine acyltransferase 2, acyl-CoA:lysophospholipid acyltransferase, acyltransferase, lysolecithin, AGPAT7, AGPAT8, Alcat1, ALE1, At1g78690, AtLPLAT2, AYTL1, AYTL2, AYTL3, CF3, CG18445, CsLPCAT, GPCAT, hPrdx6, Lclat1, LPAT, LPC acyltransferase, LPCAT, LPCAT1, LPCAT2, LPCAT3, LPCAT4, LPEAT2, LPG acyltransferase, LPGAT, LPGAT1, LPLAT, LPLAT5, lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1, LYCAT, lyso-PAF acetyltransferase, lyso-PC acyltransferase, lyso-PC acyltransferase 1, lyso-phosphatidylcholine acyltransferase 1, lysolecithin acyltransferase, lysoPC acyltransferase, lysophosphatide acyltransferase, lysophosphatidylcholine acyl transferase, lysophosphatidylcholine acyltransferase, lysophosphatidylcholine acyltransferase 1, lysophosphatidylcholine acyltransferase 3, lysophosphatidylcholine acyltransferase 4, lysophosphatidylethanolamine acyltransferase 2, lysophosphocholine acyltransferase 1, lysophosphocholine acyltransferase 2, lysophosphocholine acyltransferase 3, lysophosphocholine acyltransferase 4, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mboa-6, MBOAT protein Nes, MBOAT5, membrane-bound O-acyltransferase 5, mLPEAT2, More, mPrdx6, N-acylphosphatidylethanolamine synthase, NAPE synthase, PCAT1, PCAT2, PGAT, rPrdx6, YALI0E16797g, yeast tafazzin, Ypr140wp

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.23 1-acylglycerophosphocholine O-acyltransferase

Temperature Stability

Temperature Stability on EC 2.3.1.23 - 1-acylglycerophosphocholine O-acyltransferase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
microsomal fractions, LPCAT activity is reduced by approximately 38% after 60 min, and 16% after 15 min
37
-
oleoyl-CoA specific activity loses 50% of activity after 90 min, arachidonoyl-CoA specific activity loses 45% of activity after 90 min
43
-
half-life: 12 min
45
-
10% loss of activity after 1 min
48
-
half-life: 1 min, oleoyl-CoA specific activity
50
-
50% loss of activity after 1 min
52
-
half-life: 1 min, arachidonoyl-CoA specific activity
55
-
70% loss of activity after 3 min, t1/2 about 2 min
additional information
-
thermal stability of microsomal preparation