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2.1.1.356: [histone H3]-lysine27 N-trimethyltransferase

This is an abbreviated version!
For detailed information about [histone H3]-lysine27 N-trimethyltransferase, go to the full flat file.

Word Map on EC 2.1.1.356

Reaction

3 S-adenosyl-L-methionine +

a [histone H3]-L-lysine27
= 3 S-adenosyl-L-homocysteine +
a [histone H3]-N6,N6,N6-trimethyl-L-lysine27

Synonyms

CLF, EC 2.1.1.43, EZH1, EZH2, G9a, histone H3 K27 methyltransferase, histone H3 lysine 27 methyltransferase, histone lysine methyltransferase, HMTase, interleukin-5 response element II binding protein, KMT6, KMT6A, KMT6B, lysine-preferring HMTase, NSD2, NSD3, Polycomb repressive complex 2, PRC2, RE-IIBP, SET, SET domain histone lysine methyltransferase, SETDB1, TXR1, vSET, WHSC1/MMSET isoform RE-IIBP

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase

Source Tissue

Source Tissue on EC 2.1.1.356 - [histone H3]-lysine27 N-trimethyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
SETDB1 is strongly localized in gonocytes
Manually annotated by BRENDA team
SETDB1 expression gradually increases during testis development
Manually annotated by BRENDA team