1.14.14.99: (S)-limonene 3-monooxygenase
This is an abbreviated version!
For detailed information about (S)-limonene 3-monooxygenase, go to the full flat file.
Word Map on EC 1.14.14.99
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1.14.14.99
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mentha
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peppermint
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monoterpene
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regiospecific
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limonene-6-hydroxylase
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piperita
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spearmint
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flavor
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monoterpenoids
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citrus
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4s-limonene
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olefin
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fragrance
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agriculture
- 1.14.14.99
-
mentha
- peppermint
-
monoterpene
-
regiospecific
- limonene-6-hydroxylase
- piperita
- spearmint
-
flavor
-
monoterpenoids
-
citrus
-
4s-limonene
-
olefin
-
fragrance
- agriculture
Reaction
Synonyms
(-)-limonene 3-hydroxylase, (-)-limonene 3-monooxygenase, (-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating), (-)-limonene-3-hydroxylase, EC 1.14.13.47, L3oh, limonene-3-hydroxylase, More, oxygenase, (-)-limonene 3-mono-, PM17
ECTree
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Activating Compound
Activating Compound on EC 1.14.14.99 - (S)-limonene 3-monooxygenase
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the enzyme shows significantly enhanced activity upon RAD52 over-expression and cultivation optimization. (-)-Limonene hydroxylation is 2fold increased by RAD52 overexpression in strains PpPM17/AtCPR, expressing limonene-3-hydroxylase (PM17 isoform) and Arabidopsis thaliana cytochrome P450 reductase (CPR), while cultivation at pH 8 yields in about 55% increased isopiperitenol formation. The two effects are largely additive leading to an about 2.5fold enhanced isopiperitenol production in PpPM17/CPR-RAD52 over the starting strain/condition
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additional information
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the enzyme shows significantly enhanced activity upon RAD52 over-expression and cultivation optimization. (-)-Limonene hydroxylation is 2fold increased by RAD52 overexpression in strains PpPM17/AtCPR, expressing limonene-3-hydroxylase (PM17 isoform) and Arabidopsis thaliana cytochrome P450 reductase (CPR), while cultivation at pH 8 yields in about 55% increased isopiperitenol formation. The two effects are largely additive leading to an about 2.5fold enhanced isopiperitenol production in PpPM17/CPR-RAD52 over the starting strain/condition
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