1.14.14.147: 22alpha-hydroxysteroid 23-monooxygenase

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For detailed information about 22alpha-hydroxysteroid 23-monooxygenase, go to the full flat file.

Reaction

Synonyms

3-epi-6-deoxocathasterone 23-monooxygenase, 3-epi-6-deoxocathasterone,[reduced NADPH�hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating), CYP90C1, CYP90C1/ROTUNDIFOLIA3, CYP90D1, cytochrome P450 90C1, EC 1.14.13.112, ROT3

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.147 22alpha-hydroxysteroid 23-monooxygenase

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Results	in table
23	AA Sequence
1	Cloned(Commentary)
1	Cofactor
1	General Information
10	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
3	Organism
5	Pathway
1	pH Optimum
2	Reaction
2	Reference
9	Substrates and Products (Substrate)
8	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
10	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.14.14.147 - 22alpha-hydroxysteroid 23-monooxygenase

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SYSTEMATIC NAME

IUBMB Comments

22alpha-hydroxysteroid,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (C-23-hydroxylating)

A cytochrome P-450 (heme-thiolate) protein involved in brassinosteroid biosynthesis in plants. The enzyme has a relaxed substrate specificity, and C-23 hydroxylation can occur at different stages in the pathway. In Arabidopsis thaliana two isozymes, encoded by the CYP90C1 and CYP90D1 genes, have redundant activities.