Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.14.110: 2-hydroxy-1,4-benzoxazin-3-one monooxygenase

This is an abbreviated version!
For detailed information about 2-hydroxy-1,4-benzoxazin-3-one monooxygenase, go to the full flat file.

Reaction

3-hydroxyindolin-2-one
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

benzoxazinone N-monooxygenase, BX5, Cyp71C3, EC 1.14.13.140

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.110 2-hydroxy-1,4-benzoxazin-3-one monooxygenase

Inhibitors

Inhibitors on EC 1.14.14.110 - 2-hydroxy-1,4-benzoxazin-3-one monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
5 mM inhibits activity by 57%
Ca2+
-
5 mM Ca2+ inhibits activity by 69%
carbon monoxide
-
the effect of carbon monoxide can be reversed by exposing the enzyme to 450 nanometer light during the incubation period
cytochrome c
-
-
Fe2+
-
5 mM Fe2+ inhibits activity by 64%
Hg2+
-
complete inhibition at 5 mM
Mg2+
-
5 mM Mg2+ inhibits activity by 45%
Mn2+
-
complete inhibition at 5 mM
N-ethylmaleimide
-
5 mM inhibits activity by 97%
N2
-
the effect of nitrogen can be reversed by exposing the enzyme to air
NADP+
-
-
NaN3
-
5 mM NaN3 inhibits activity by 16%
p-chloromercuribenzoate
-
5 mM inhibits activity by 58%
Zn2+
-
complete inhibition at 5 mM