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1.14.13.248: L-aspartate N-monooxygenase (nitrosuccinate-forming)

This is an abbreviated version!
For detailed information about L-aspartate N-monooxygenase (nitrosuccinate-forming), go to the full flat file.

Reaction

(2S)-2-nitrosobutanedioate
+
NADPH
+
H+
+
O2
=
(2S)-2-nitrobutanedioate
+
NADP+
+
H2O

Synonyms

BN159_4422, creE

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.248 L-aspartate N-monooxygenase (nitrosuccinate-forming)

Systematic Name

Systematic Name on EC 1.14.13.248 - L-aspartate N-monooxygenase (nitrosuccinate-forming)

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SYSTEMATIC NAME
IUBMB Comments
L-aspartate,NADPH:oxygen oxidoreductase [(2S)-2-nitrobutanedioate-forming]
The enzyme, found in some Actinobacteria, is involved in a pathway that forms nitrite, which is subsequently used to generate a diazo group in some secondary metabolites. Requires an FAD cofactor.