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1.14.13.248: L-aspartate N-monooxygenase (nitrosuccinate-forming)

This is an abbreviated version!
For detailed information about L-aspartate N-monooxygenase (nitrosuccinate-forming), go to the full flat file.

Reaction

(2S)-2-nitrosobutanedioate
+
NADPH
+
H+
+
O2
=
(2S)-2-nitrobutanedioate
+
NADP+
+
H2O

Synonyms

BN159_4422, creE

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.248 L-aspartate N-monooxygenase (nitrosuccinate-forming)

General Information

General Information on EC 1.14.13.248 - L-aspartate N-monooxygenase (nitrosuccinate-forming)

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
CreE catalyzes iterative oxidation of L-aspartic acid to nitrosuccinic acid via N-hydroxyaspartic acid and nitrososuccinic acid. When CreE and CreD are incubated with L-aspartic acid, nitrous acid is the product. CreD accepts nitrosuccinic acid as a substrate only when it is directly delivered by CreE immediately after its synthesis. Both are involved in cremeomycin biosynthesis
physiological function