1.1.1.26: glyoxylate reductase
This is an abbreviated version!
For detailed information about glyoxylate reductase, go to the full flat file.
Word Map on EC 1.1.1.26
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1.1.1.26
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hyperoxalurias
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oxalate
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ph2
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stone
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nephrolithiasis
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nephrocalcinosis
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l-glycerate
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photorespiratory
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alanine:glyoxylate
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urolithiasis
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4-hydroxy-2-oxoglutarate
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glyrs
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diagnostics
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medicine
- 1.1.1.26
- hyperoxalurias
- oxalate
- ph2
- stone
- nephrolithiasis
- nephrocalcinosis
- l-glycerate
-
photorespiratory
-
alanine:glyoxylate
-
urolithiasis
- 4-hydroxy-2-oxoglutarate
- glyrs
- diagnostics
- medicine
Reaction
Synonyms
GHPR, glycerate dehydrogenase, glycolate oxidase, glyoxylate reductase isoform 1, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate/hydroxypyruvate reductase, glyoxylic acid reductase, GLYR1, GLYR2, GRHPR, GxrA, HPR1, NADH-dependent glyoxylate reductase, NADH-glyoxylate reductase, reductase, glyoxylate, SSO3187, succinic semialdehyde/glyoxylate reductase
ECTree
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Cloned
Cloned on EC 1.1.1.26 - glyoxylate reductase
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exclusive localization in the cytosol of transgenic Arabidopsis plants co-expressing GFP-GLYR1 and and Cherry-PTS1, a fusion protein consisting of the Cherry fluorescent protein linked to the PTS1 of the peroxisomal enzyme hydroxypyruvate reductase. Expression of N-terminal GFP-tagged or Myc-tagged GLYR1 in tobacco BY-2 cell cytosol. GFP- or Myc-tagged GLYR1 is competent, at least partially, for import into peroxisomes, since replacement of the C-terminal glutamate in GLYR1 with leucine, which yields a canonical PTS1 (i.e., a C-terminal small-basic-hydrophobic tripeptide motif), results in the modified fusion protein (GFPGLYR1-E to L and Myc-GLYR1-E to L) being dual localized to the cytosol and peroxisomes in BY-2 cells
expression in Epicurean coli BL21 (DE3) as fusion protein from a His-tag plasmid
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gene gxrA, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression of His-tagged enzyme in Escherichia coli strain BL21
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