EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.3.1.B46 | 1-acylglycerophosphatidylinositol o-acyltransferase deficiency |
23097495 |
LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice. |
causal interaction
unassigned |
4
0 |
| 2.3.1.B46 | 1-acylglycerophosphatidylinositol o-acyltransferase deficiency |
32591434 |
Loss of hepatic Mboat7 leads to liver fibrosis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
1
3
1 |
| 2.3.1.B46 | 1-acylglycerophosphatidylinositol o-acyltransferase deficiency |
32645526 |
Identification of novel loss of function variants in MBOAT7 resulting in intellectual disability. |
causal interaction
unassigned |
4
0 |
| 2.3.1.B46 | Adenocarcinoma |
31928970 |
The MBOAT7 rs641738 variant is associated with an improved outcome in primary sclerosing cholangitis. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
4
0 |
| 2.3.1.B46 | Carcinogenesis |
32034305 |
The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 2.3.1.B46 | Carcinoma, Hepatocellular |
28674415 |
MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals. |
diagnostic usage
unassigned |
1
0 |
| 2.3.1.B46 | Carcinoma, Hepatocellular |
30506232 |
Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma. |
diagnostic usage
ongoing research
unassigned |
2
1
0 |
| 2.3.1.B46 | Carcinoma, Hepatocellular |
31928970 |
The MBOAT7 rs641738 variant is associated with an improved outcome in primary sclerosing cholangitis. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
1
4
0 |
| 2.3.1.B46 | Cardiovascular Diseases |
31851849 |
Metabolic syndrome but not genetic polymorphisms known to induce NAFLD predicts increased total mortality in subjects with NAFLD (OPERA study). |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
3
1
0 |
| 2.3.1.B46 | Cholangitis, Sclerosing |
31924553 |
The MBOAT7 rs641738 variant in primary sclerosing cholangitis: A novel biomarker for prognostication. |
unassigned |
0 |
