EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.1.1.148 | Communicable Diseases |
30702807 |
Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase?X. |
therapeutic application
unassigned |
4
0 |
| 2.1.1.148 | Hypersensitivity |
25544046 |
The complex mechanism of antimycobacterial action of 5-fluorouracil. |
unassigned |
0 |
| 2.1.1.148 | Tuberculosis |
16139296 |
Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution. |
unassigned |
0 |
| 2.1.1.148 | Tuberculosis |
18192395 |
Functional analysis of the Mycobacterium tuberculosis FAD-dependent thymidylate synthase, ThyX, reveals new amino acid residues contributing to an extended ThyX motif. |
unassigned |
0 |
| 2.1.1.148 | Tuberculosis |
21657202 |
Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 2.1.1.148 | Tuberculosis |
26482569 |
Synthesis and evaluation of C-5 modified 2'-deoxyuridine monophosphates as inhibitors of M. tuberculosis thymidylate synthase. |
therapeutic application
unassigned |
3
0 |
| 2.1.1.148 | Tuberculosis |
27283217 |
Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis. |
ongoing research
unassigned |
2
0 |
| 2.1.1.148 | Tuberculosis |
28359706 |
Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile. |
therapeutic application
unassigned |
4
0 |
| 2.1.1.148 | Tuberculosis |
30702807 |
Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase?X. |
therapeutic application
unassigned |
4
0 |
| 2.1.1.148 | Tuberculosis |
30792519 |
Novel 5-substituted derivatives of 2'-deoxy-6-azauridine with antibacterial activity. |
therapeutic application
unassigned |
1
0 |
