EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.18.2 | Atherosclerosis |
31332008 |
Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms. |
ongoing research
unassigned |
2
0 |
| 1.14.18.2 | Brain Neoplasms |
9108463 |
Ganglioside biosynthetic gene expression in experimental mouse brain tumors. |
causal interaction
ongoing research
unassigned |
1
4
0 |
| 1.14.18.2 | cmp-n-acetylneuraminate monooxygenase deficiency |
21350118 |
Pancreatic {beta}-cell failure in obese mice with human-like CMP-Neu5Ac hydroxylase deficiency. |
causal interaction
unassigned |
4
0 |
| 1.14.18.2 | Diabetes Mellitus, Type 2 |
25243123 |
MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling. |
ongoing research
unassigned |
3
0 |
| 1.14.18.2 | Endotoxemia |
28148732 |
Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State. |
therapeutic application
unassigned |
1
0 |
| 1.14.18.2 | Glucose Intolerance |
25243123 |
MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling. |
ongoing research
unassigned |
3
0 |
| 1.14.18.2 | Hearing Loss |
26319214 |
Oxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing loss. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
1
0 |
| 1.14.18.2 | Hearing Loss |
31149396 |
Cmah deficiency may lead to age-related hearing loss by influencing miRNA-PPAR mediated signaling pathway. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 1.14.18.2 | Hyperglycemia |
25243123 |
MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling. |
ongoing research
unassigned |
3
0 |
| 1.14.18.2 | Infections |
30862964 |
Intestine specific regulation of pig cytidine-5'-monophospho-N-acetylneuraminic acid hydroxylase gene for N-glycolylneuraminic acid biosynthesis. |
unassigned |
0 |
