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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.1.1.B118physiological function loss of STRM-1 function leads to elevated levels of dafachronic acid and inefficient stress-resistant dauer larva formation. Methylated sterols are strongly elevated in dauer larvae, and Strm-.1 acts downstream of DAF-9 and DAf-12 756549
Display the reaction diagram Show all sequences 2.1.1.B118physiological function reaction mechanism of C4-methyl sterol formation is a two-step process of bound 3-oxo sterol undergoing active site isomerization to the 4-enol intermediate that is methylated by SAM in a stereoselective manner to yield the C4alpha- (equatorial) methyl group, followed by rearrangement of the enol back to the 3-oxo form 757381
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