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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 1.14.14.183physiological function biosynthesis of the taxol in yew species involves eight cytochrome P450-mediated oxygenations and four coenzyme A-dependent acylations of the diterpenoid core. Taxusin (taxa-4(20),11(12)-dien-5alpha,9alpha,10beta,13alpha-tetraol tetraacetate) is used as a surrogate substrate for identification and characterization 764450
Display the reaction diagram Show all sequences 1.14.14.183physiological function taxusin is hydroxylated by both taxoid 7beta-hydroxylase and taxoid 2alpha-hydroxylase, and both enzymes are capable of the reciprocal conversion of their respective pentaol tetraacetate products to the hexaol tetraacetate 764008
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