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Literature summary for 1.14.14.183 extracted from

  • Chau, M.; Jennewein, S.; Walker, K.; Croteau, R.
    Taxol biosynthesis Molecular cloning and characterization of a cytochrome P450 taxoid 7beta-hydroxylase (2004), Chem. Biol., 11, 663-672 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Taxus cuspidata
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General Information

General Information Comment Organism
physiological function biosynthesis of the taxol in yew species involves eight cytochrome P450-mediated oxygenations and four coenzyme A-dependent acylations of the diterpenoid core. Taxusin (taxa-4(20),11(12)-dien-5alpha,9alpha,10beta,13alpha-tetraol tetraacetate) is used as a surrogate substrate for identification and characterization Taxus cuspidata