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EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.34up UBE2M is a stress-inducible gene subjected to cis-trans-activation by hypoxia-inducible factor-1alpha and transcription factor AP-1. MLN4924, a small molecule inhibitor of E1 NEDD8-activating enzyme, up-regulates UBE2M via blocking degradation of hypoxia-inducible factor-1alpha and transcription factor AP-1 757651
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