EC Number   |
Activating Compound |
Reference |
|---|
   1.17.3.2 | acetonitrile |
- |
702182 |
| 1.17.3.2 | allopurinol |
inhibits xanthine and hypoxanthine oxidation in vivo in intestine and pancreas, but enhances the activity in liver, tissue-dependent effects, overview |
703310 |
| 1.17.3.2 | angiotensin II |
Ang II substantially increases endothelial enzyme protein levels and enzyme-dependent superoxide production in cultured endothelial cells |
684783 |
| 1.17.3.2 | apigenin |
increases liver xanthine oxidase activities significantly, but has no effect on serum xanthine oxidase activities |
715069 |
| 1.17.3.2 | apoptotic lymphocyte microparticles |
microparticles are membrane vesicles released during cell activation and apoptosis, they activate reactive oxygen species production by xanthine oxidase in endothelial cells and aorta, inhibition of phosphoinositol 3-kinase enhances the activating effect, xanthine oxidase inhibitors reduce it, overview |
688155 |
| 1.17.3.2 | ascorbate |
in absence of thiols or ascorbate, no NO generation is detected from xanthine oxidase mediated organic nitrate reduction |
659465 |
| 1.17.3.2 | astilbin |
significantly increases serum xanthine oxidase activities, and decreases liver xanthine oxidase activities significantly |
715069 |
| 1.17.3.2 | dimethylformamide |
highly stimulating |
702182 |
| 1.17.3.2 | dioxane |
- |
702182 |
| 1.17.3.2 | diphenylene iodonium chloride |
strongly inhibits xanthine oxidase mediated NO generation with NADH serving as reducing substrate, with xanthine or 2,3-dihydroxybenzaldehyde as reducing substrates, NO generation is increased more than six times |
659326 |
