Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iso-pentylsarin | - |
Homo sapiens | |
additional information | pentylsarin derivative inhibitors, structure-activity relationship and inhibition kinetics, overview | Homo sapiens | |
n-pentylsarin | - |
Homo sapiens | |
neo-pentylsarin | - |
Homo sapiens | |
sec-pentylsarin | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylthiocholine + H2O | - |
Homo sapiens | acetate + thiocholine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | rate constants for the inhibition of human erythrocyte AChE by four pentylsarin compounds (ki), for the spontaneous dealkylation (aging, ka) and reactivation (ks) of inhibited AChE as well as for the oximeinduced reactivation of inhibited AChE by obidoxime and HI 6 reflected by the dissociation constant (KD) and the reactivity constant (kr), overview | Homo sapiens |