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Literature summary for 3.1.1.7 extracted from
- Concentration-dependent kinetics of acetylcholinesterase inhibition by the organophosphate paraoxon (2006), Toxicol. Sci., 90, 460-469.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| chlorpyrifos oxon | - |
Homo sapiens |  |
| paraoxon | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
recombinant protein | - |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| acetylcholine + H2O = choline + acetate | computer-modelled comparison of ordered uni bi and ki kinetic mechanism. ki model is accurate at equilibrium and when the inhibitor concentration is well below its Kd value | Homo sapiens |
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