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Literature summary for 2.1.1.354 extracted from
- Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan (2017), Nature, 544, 185-190 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 | Caenorhabditis elegans | overall reaction | 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 | overall reaction | Caenorhabditis elegans | 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| COMPASS chromatin complex | - |
Caenorhabditis elegans |
| H3K4me3 methyltransferase | - |
Caenorhabditis elegans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | an enzyme deficiency promotes fat accumulation in worms with a specific enrichment of mono-unsaturated fatty acids | Caenorhabditis elegans |
| physiological function | the enzyme regulates lifespan in Caenorhabditis elegans | Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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