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Disease on EC 2.4.1.12 - cellulose synthase (UDP-forming)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Aspergillosis
Arundifungin, a novel antifungal compound produced by fungi: biological activity and taxonomy of the producing organisms.
Correlation of cilofungin in vivo efficacy with its activity against Aspergillus fumigatus (1,3)-beta-D-glucan synthase.
SCY-078, a Novel Oral Glucan Synthase Inhibitor, for the Treatment of Invasive Aspergillosis: Evaluation of Antifungal Activity Singly and in Combination.
Candidiasis
Arundifungin, a novel antifungal compound produced by fungi: biological activity and taxonomy of the producing organisms.
In vivo pharmacodynamics of HMR 3270, a glucan synthase inhibitor, in a murine candidiasis model.
Candidiasis, Invasive
Oral glucan synthase inhibitor SCY-078 is effective in an experimental murine model of invasive candidiasis caused by WT and echinocandin-resistant Candida glabrata.
Penetration of Ibrexafungerp (Formerly SCY-078) at the Site of Infection in an Intra-abdominal Candidiasis Mouse Model.
Pharmacodynamic Target Evaluation of a Novel Oral Glucan Synthase Inhibitor, SCY-078 (MK-3118), Using an In Vivo Murine Invasive Candidiasis Model.
Candidiasis, Vulvovaginal
A Novel 1,3-Beta-d-Glucan Inhibitor, Ibrexafungerp (Formerly SCY-078), Shows Potent Activity in the Lower pH Environment of Vulvovaginitis.
Cysts
?-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and Eimeria.
Down-regulation of cellulose synthase inhibits the formation of endocysts in Acanthamoeba.
Dehydration
Changes in secondary metabolites and fiber quality of cotton (Gossypium hirsutum) seed under consecutive water stress and in silico analysis of cellulose synthase and xyloglucan endotransglucosylase.
Dwarfism
Mapping of a Cellulose-Deficient Mutant Named dwarf1-1 in Sorghum bicolor to the Green Revolution Gene gibberellin20-oxidase Reveals a Positive Regulatory Association between Gibberellin and Cellulose Biosynthesis.
Hypersensitivity
The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways.
Infections
Correlation of cilofungin in vivo efficacy with its activity against Aspergillus fumigatus (1,3)-beta-D-glucan synthase.
Evidence of a Cellulosic Layer in Pandoravirus massiliensis Tegument and the Mystery of the Genetic Support of Its Biosynthesis.
Identification of Genes Expressed Differentially in Grapefruit Infected with Candidatus Liberibacter asiaticus in the Late Stage of Disease
Resistance to echinocandin-class antifungal drugs.
Small RNA inhibits infection by downy mildew pathogen Hyaloperonospora arabidopsidis.
Mycoses
Clinical Pharmacokinetics and Drug-Drug Interaction Potential for Coadministered SCY-078, an Oral Fungicidal Glucan Synthase Inhibitor, and Tacrolimus.
Penetration of Ibrexafungerp (Formerly SCY-078) at the Site of Infection in an Intra-abdominal Candidiasis Mouse Model.
Phenylketonurias
Patient's thoughts and expectations about centres of expertise for PKU.
Scabies
Contribution of the ?-glucosidase BglC to the onset of the pathogenic lifestyle of Streptomyces scabies.
Starvation
AtCSLD3 and GhCSLD3 mediate root growth and cell elongation downstream of the ethylene response pathway in Arabidopsis.