Reference on EC 2.3.1.61 - dihydrolipoyllysine-residue succinyltransferase
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Reed, L.J.; Cox, D.J.
Multienzyme complexes
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
1
213-240
1970
Bos taurus, Escherichia coli, Sus scrofa
-
De Kok, A.; Kornfeld, S.; Benziman, M.; Milner, Y.
Subunit composition and partial reactions of the 2-oxoglutarate dehydrogenase complex of Acetobacter xylinum
Eur. J. Biochem.
106
49-58
1980
Komagataeibacter xylinus
Pettit, F.H.; Hamilton, L.; Munk, P.; Namihira, G.; Eley, M.H.; Willms, C.R.; Reed, L.J.
alpha-Keto acid dehydrogenase complexes. XIX. Subunit structure of the Escherichia coli alpha-ketoglutarate dehydrogenase complex
J. Biol. Chem.
248
5282-5290
1973
Escherichia coli
Hein, S.; Steinbuechel, A.
Cloning and characterization of the Alcaligenes eutrophus 2-oxoglutarate dehydrogenase complex
FEMS Microbiol. Lett.
136
231-238
1996
Cupriavidus necator, Bacillus subtilis (P16263), Saccharomyces cerevisiae (P19262), Azotobacter vinelandii (P20708), Rattus norvegicus (Q01205)
Derosier, D.J.; Oliver, R.M.; Reed, L.J.
Crystallization and preliminary structural analysis of dihydrolipoyl transsuccinylase, the core of the 2-oxoglutarate dehydrogenase complex
Proc. Natl. Acad. Sci. USA
68
1135-1137
1971
Escherichia coli
Hall, E.R.; Weitzman, P.D.J.
A continuous spectrophotometric assay for the transacylase (E2) component of pyruvate and alpha-oxoglutarate dehydrogenase enzyme complexes
Anal. Biochem.
62
286-290
1974
Acinetobacter lwoffii
Tanaka, N.; Koike, K.; Otsuka, K.I.; Hamada, M.; Ogasahara, K.; Koike, M.
Mammalian alpha-keto acid dehydrogenase complexes. 8. Properties and subunit composition of the pig heart lipoate succinyltransferase
J. Biol. Chem.
249
191-198
1974
Sus scrofa
Angelides, K.J.; Hammes, G.G.
Structural and mechanistic studies of the alpha-ketoglutarate dehydrogenase multienzyme complex from Escherichia coli
Biochemistry
18
5531-5537
1979
Escherichia coli
White, R.H.; Bleile, D.M.; Reed, L.J.
Lipoic acid content of dihydrolipoyl transacylases determined by isotope dilution analysis
Biochem. Biophys. Res. Commun.
94
78-84
1980
Bos taurus, Escherichia coli
Robien, M.A.; Clore, G.M.; Omichinski, J.G.; Perham, R.N.; Appella, E.; Sakaguchi, K.; Gronenborn, A.M.
Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli
Biochemistry
31
3463-3471
1992
Escherichia coli
Nakano, K.; Takase, C.; Sakamoto, T.; Nakagawa, S.; Inazawa, J.; Ohta, S.; Matuda, S.
Isolation, characterization and structural organization of the gene and pseudogene for the dihydrolipoamide succinyltransferase component of the human 2-oxoglutarate dehydrogenase complex
Eur. J. Biochem.
224
179-189
1994
Homo sapiens
Takase, C.; Nakano, K.; Ohta, S.; Nakagawa, S.; Matuda, S.
Different distribution of dihydrolipoamide succinyltransferase, dihydrolipoamide acetyltransferase and ATP synthase beta-subunit in monkey brain
In Vivo
10
495-502
1996
Macaca fuscata, Saccharomyces cerevisiae
Matuda, S.; Kodama, J.; Goshi, N.; Takase, C.; Nakano, K.; Nakagawa, S.; Ohta, S.
A polypeptide derived from mitochondrial dihydrolipoamide succinyltransferase is located on the plasma membrane in skeletal muscle
Biochem. Biophys. Res. Commun.
241
151-156
1997
Homo sapiens, Rattus norvegicus
Koike, K.; Ishibashi, H.; Koike, M.
Immunoreactivity of porcine heart dihydrolipoamide acetyl- and succinyl-transferases (PDC-E2, OGDC-E2) with primary biliary cirrhosis sera: characterization of the autoantigenic region and effects of enzymic delipoylation and relipoylation
Hepatology
27
1467-1474
1998
Bos taurus, Escherichia coli, Homo sapiens, Sus scrofa
Nguyen, S.V.; To, H.; Yamaguchi, T.; Fukushi, H.; Hirai, K.
Characterization of the Coxiella burnetii sucB gene encoding an immunogenic dihydrolipoamide succinyltransferase
Microbiol. Immunol.
43
743-749
1999
Escherichia coli, Coxiella burnetii (Q9RH46), Coxiella burnetii
Knapp, J.E.; Carroll, D.; Lawson, J.E.; Ernst, S.R.; Reed, L.J.; Hackert, M.L.
Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase
Protein Sci.
9
37-48
2000
Azotobacter vinelandii, Cupriavidus necator, Geobacillus stearothermophilus, Saccharomyces cerevisiae, Enterococcus faecalis, Haemophilus influenzae, Homo sapiens, Pseudomonas aeruginosa, Escherichia coli (P0AFG6), Escherichia coli, Corynebacterium glutamicum (Q8NNJ2)
Koike, K.; Suematsu, T.; Ehara, M.
Cloning, overexpression and mutagenesis of cDNA encoding dihydrolipoamide succinyltransferase component of the porcine 2-oxoglutarate dehydrogenase complex
Eur. J. Biochem.
267
3005-3016
2000
Azotobacter vinelandii, Bacillus subtilis, Bos taurus, Enterococcus faecalis, Escherichia coli, Homo sapiens, Rattus norvegicus, Saccharomyces cerevisiae, Sus scrofa
Zygmunt, M.S.; Diaz, M.A.; Teixeira-Gomes, A.P.; Cloeckaert, A.
Cloning, nucleotide sequence, and expression of the Brucella melitensis sucB gene coding for an immunogenic dihydrolipoamide succinyltransferase homologous protein
Infect. Immun.
69
6537-6540
2001
Brucella abortus, Brucella anthropi, Phyllobacterium myrsinacearum, Escherichia coli (P0AFG6), Escherichia coli, Brucella melitensis (Q9L6H8), Brucella melitensis, Brucella melitensis 16M (Q9L6H8), Brucella abortus S19
Kanamori, T.; Nishimaki, K.; Asoh, S.; Ishibashi, Y.; Takata, I.; Kuwabara, T.; Taira, K.; Yamaguchi, H.; Sugihara, S.; Yamazaki, T.; Ihara, Y.; Nakano, K.; Matuda, S.; Ohta, S.
Truncated product of the bifunctional DLST gene involved in biogenesis of the respiratory chain
EMBO J.
22
2913-2923
2003
Homo sapiens
Gilmore, R.D., Jr.; Carpio, A.M.; Kosoy, M.Y.; Gage, K.L.
Molecular characterization of the sucB gene encoding the immunogenic dihydrolipoamide succinyltransferase protein of Bartonella vinsonii subsp. berkhoffii and Bartonella quintana
Infect. Immun.
71
4818-4822
2003
Bartonella quintana (Q6FYD4), Bartonella quintana, Bartonella vinsonii (Q8GCY1)
MacDonald, M.J.; Husain, R.D.; Hoffmann-Benning, S.; Baker, T.R.
Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0
J. Biol. Chem.
279
27278-27285
2004
Homo sapiens, Rattus norvegicus
Litwin, C.M.; Johnson, J.M.; Martins, T.B.
The Bartonella henselae sucB gene encodes a dihydrolipoamide succinyltransferase protein reactive with sera from patients with cat-scratch disease
J. Med. Microbiol.
53
1221-1227
2004
Bartonella henselae
Kabeya, H.; Maruyama, S.; Hirano, K.; Mikami, T.
Cloning and expression of Bartonella henselae sucB gene encoding an immunogenic dihydrolipoamide succinyltransferase homologous protein
Microbiol. Immunol.
47
571-576
2003
Bartonella henselae
Ohta, S.; Ohsawa, I.
Dysfunction of mitochondria and oxidative stress in the pathogenesis of Alzheimers disease: on defects in the cytochrome c oxidase complex and aldehyde detoxification
J. Alzheimers Dis.
9
155-166
2006
Homo sapiens
Cisar, C.R.; Balog, J.M.; Anthony, N.B.; Donoghue, A.M.
Differential expression of cardiac muscle mitochondrial matrix proteins in broilers from ascites-resistant and susceptible lines
Poult. Sci.
84
704-708
2005
Gallus gallus
Dumont, M.; Ho, D.J.; Calingasan, N.Y.; Xu, H.; Gibson, G.; Beal, M.F.
Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition
Free Radic. Biol. Med.
47
1019-1027
2009
Homo sapiens
Yang, L.; Shi, Q.; Ho, D.J.; Starkov, A.A.; Wille, E.J.; Xu, H.; Chen, H.L.; Zhang, S.; Stack, C.M.; Calingasan, N.Y.; Gibson, G.E.; Beal, M.F.
Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins
Neurobiol. Dis.
36
320-330
2009
Mus musculus
Hoffelder, M.; Raasch, K.; van Ooyen, J.; Eggeling, L.
The E2 domain of OdhA of Corynebacterium glutamicum has succinyltransferase activity dependent on lipoyl residues of the acetyltransferase AceF
J. Bacteriol.
192
5203-5211
2010
Corynebacterium glutamicum (Q8NNJ2)
Guo, H.; Madzak, C.; Du, G.; Zhou, J.
Mutagenesis of conserved active site residues of dihydrolipoamide succinyltransferase enhances the accumulation of alpha-ketoglutarate in Yarrowia lipolytica
Appl. Microbiol. Biotechnol.
100
649-659
2016
Yarrowia lipolytica (Q6C5L8), Yarrowia lipolytica, Yarrowia lipolytica E 150 (Q6C5L8)
Kessler, M.; Berger, I.M.; Just, S.; Rottbauer, W.
Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish
Basic Res. Cardiol.
110
14
2015
Danio rerio
Andi, B.; Soares, A.S.; Shi, W.; Fuchs, M.R.; McSweeney, S.; Liu, Q.
Structure of the dihydrolipoamide succinyltransferase catalytic domain from Escherichia coli in a novel crystal form a tale of a common protein crystallization contaminant
Acta Crystallogr. Sect. F
75
616-624
2019
Escherichia coli (P0AFG6), Escherichia coli
Guo, H.; Madzak, C.; Du, G.; Zhou, J.
Mutagenesis of conserved active site residues of dihydrolipoamide succinyltransferase enhances the accumulation of alpha-ketoglutarate in Yarrowia lipolytica
Appl. Microbiol. Biotechnol.
100
649-659
2016
Yarrowia lipolytica, Yarrowia lipolytica WSH-Z06
Heggermont, W.A.; Papageorgiou, A.P.; Quaegebeur, A.; Deckx, S.; Carai, P.; Verhesen, W.; Eelen, G.; Schoors, S.; van Leeuwen, R.; Alekseev, S.; Elzenaar, I.; Vinckier, S.; Pokreisz, P.; Walravens, A.S.; Gijsbers, R.; Van Den Haute, C.; Nickel, A.; Schroen, B.; van Bilsen, M.; Janssens, S.; Maack, C.; Pinto, Y.; Carmeliet, P.; Heymans, S.
Inhibition of microRNA-146a and overexpression of its target dihydrolipoyl succinyltransferase protect against pressure overload-induced cardiac hypertrophy and dysfunction
Circulation
136
747-761
2017
Mus musculus (Q9D2G2), Mus musculus
Chakraborty, J.; Nemeria, N.S.; Farinas, E.; Jordan, F.
Catalysis of transthiolacylation in the active centers of dihydrolipoamide acyltransacetylase components of 2-oxo acid dehydrogenase complexes
FEBS Open Bio
8
880-896
2018
Escherichia coli (P0AFG6), Escherichia coli
Chen, B.; Long, Q.; Zhao, Y.; Wu, Y.; Ge, S.; Wang, P.; Yang, C.G.; Chi, Y.; Song, B.; Yang, S.
Sulfone-based probes unraveled dihydrolipoamide S-succinyltransferase as an unprecedented target in phytopathogens
J. Agric. Food Chem.
67
6962-6969
2019
Xanthomonas citri, Xanthomonas oryzae pv. oryzae, Xanthomonas oryzae pv. oryzae PXO99A, Xanthomonas citri 29-1
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