2.3.1.24: sphingosine N-acyltransferase
This is an abbreviated version!
For detailed information about sphingosine N-acyltransferase, go to the full flat file.
Word Map on EC 2.3.1.24
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2.3.1.24
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sphingolipids
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fumonisins
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sphingoid
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synthases
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sphingomyelin
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sphingomyelinase
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mycotoxin
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fusarium
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palmitoyltransferase
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dihydroceramide
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glucosylceramide
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verticillioides
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ceramidase
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n-acylation
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moniliforme
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sphingosine-1-phosphate
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myriocin
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glycosphingolipids
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llc-pk1
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phytosphingosine
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fb1-induced
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c16-ceramide
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corn-based
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medicine
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smases
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very-long-chain
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analysis
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fenretinide
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glccers
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dihydrosphingosine
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ceramide-induced
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diagnostics
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l-cycloserine
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acyl-coa-dependent
- 2.3.1.24
- sphingolipids
- fumonisins
-
sphingoid
- synthases
- sphingomyelin
- sphingomyelinase
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mycotoxin
- fusarium
- palmitoyltransferase
- dihydroceramide
- glucosylceramide
- verticillioides
- ceramidase
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n-acylation
- moniliforme
- sphingosine-1-phosphate
- myriocin
- glycosphingolipids
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llc-pk1
- phytosphingosine
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fb1-induced
- c16-ceramide
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corn-based
- medicine
- smases
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very-long-chain
- analysis
- fenretinide
- glccers
- dihydrosphingosine
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ceramide-induced
- diagnostics
- l-cycloserine
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acyl-coa-dependent
Reaction
Synonyms
(dihydro)ceramide synthase, acyl-CoA : sphingosine N-acyltramferase, acyl-CoA : sphingosine N-acyltransferase, acyltransferase, sphingosine, C16:0-CerS, CER2, Cer3, ceramide synthase, ceramide synthase 4, ceramide synthase 5, ceramide synthase 6, ceramide synthetase, CerS, CerS4, CerS45, CerS5, CerS6, CNAG_02086, CNAG_02087, CNAG_06717, DLag1, Drosophila longevitiy assurance gene-1 homologue, fatty acyl-CoA:sphingosine acyltransferase, LAC1, LAG1, LAG1 longevity assurance homolog 2, LAG1 longevity assurance homolog 5, LAG12, LASS5, Lass6, LOH2, longevity assurance homolog 5, longevity assurance homolog 6, longevity assurance homologue 5, longevity assurance homologue 6, More, schlank, SpAT, sphinganine N-acyl transferase synthase, sphinganine N-acyltransferase, sphingosine acyltransferase, sphingosine N-acyltransferase, sphingosine/sphinganine acyltransferase, TcCerS, TcCERS1, TRAM homolog 4, translocating chain-associating membrane protein homolog 4, trh1-like, trh4
ECTree
2.3.1.24 sphingosine N-acyltransferaseAdvanced search results
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results (Source Tissue
Source Tissue on EC 2.3.1.24 - sphingosine N-acyltransferase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
isozymes CerS2 (EC 2.3.1.297) and CerS6 (EC 2.3.1.24) mRNA is significantly elevated in breast cancer tissue compared to normal tissue, with approximately half of the individuals showing elevated CerS2 and CerS6 mRNA. A significant correlation is found between CerS2 and CerS6 isozyme expression, and between isozymes CerS4 (EC 2.3.1.24) and CerS2/CerS6 expression
human hepatoma HepG2 cells stably transfected with recombinant plasmids carrying the murine alcohol dehydrogenase gene and the human cytochrome P450 2E1 gene, in vitro model of alcoholic steatosis
epidermal, expression analysis of the CerS family members during keratinocyte differentiation, overview
additional information
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia
high enzyme expression level, pulmonary LASS5 is developmentally regulated, but its expression is spatially and gender-nonspecific
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high enzyme expression level, pulmonary LASS5 is developmentally regulated, but its expression is spatially and gender-nonspecific
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CerS2 and CerS6 are the major very long-chain and long-chain CerS isoforms in MCF-7 cells, respectively
additional information
in primary type II epithelial cells, murine lung fibroblasts, and MLE cells, LASS5 is the predominant ceramide synthase species identified
additional information
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in primary type II epithelial cells, murine lung fibroblasts, and MLE cells, LASS5 is the predominant ceramide synthase species identified
additional information
isozymes mRNAs for Lass2, Lass4, Lass5 and Lass6 are found to be mostly ubiquitous, although no expression is detected in muscle for any of these. No expression of Lass6 is observed in heart, muscle, spleen or stomach. Lass6 is most highly expressed in kidney, followed by brain
additional information
isozymes mRNAs for Lass2, Lass4, Lass5 and Lass6 are found to be mostly ubiquitous, although no expression is detected in muscle for any of these. No expression of Lass6 is observed in heart, muscle, spleen or stomach. Lass6 is most highly expressed in kidney, followed by brain
additional information
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isozymes mRNAs for Lass2, Lass4, Lass5 and Lass6 are found to be mostly ubiquitous, although no expression is detected in muscle for any of these. No expression of Lass6 is observed in heart, muscle, spleen or stomach. Lass6 is most highly expressed in kidney, followed by brain
additional information
isozymes mRNAs for Lass2, Lass4, Lass5 and Lass6 are found to be mostly ubiquitous, although no expression is detected in muscle for any of these. The highest expression of Lass5 is in testis, and the expression in kidney is also high
additional information
isozymes mRNAs for Lass2, Lass4, Lass5 and Lass6 are found to be mostly ubiquitous, although no expression is detected in muscle for any of these. The highest expression of Lass5 is in testis, and the expression in kidney is also high
additional information
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isozymes mRNAs for Lass2, Lass4, Lass5 and Lass6 are found to be mostly ubiquitous, although no expression is detected in muscle for any of these. The highest expression of Lass5 is in testis, and the expression in kidney is also high
additional information
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in primary type II epithelial cells, murine lung fibroblasts, and MLE cells, LASS5 is the predominant ceramide synthase species identified
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