Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.3.1.237: neocarzinostatin naphthoate synthase

This is an abbreviated version!
For detailed information about neocarzinostatin naphthoate synthase, go to the full flat file.

Reaction

acetyl-CoA
+ 5 malonyl-CoA + 2 NADPH + 2 H+ =
2-hydroxy-5-methyl-1-naphthoate
+ 6 CoA + 5 CO2 + 3 H2O + 2 NADP+

Synonyms

naphthoic acid synthase, ncsB, NNS

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.237 neocarzinostatin naphthoate synthase

Reference

Reference on EC 2.3.1.237 - neocarzinostatin naphthoate synthase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sthapit, B.; Oh, T.J.; Lamichhane, R.; Liou, K.; Lee, H.C.; Kim, C.G.; Sohng, J.K.
Neocarzinostatin naphthoate synthase: an unique iterative type I PKS from neocarzinostatin producer Streptomyces carzinostaticus
FEBS Lett.
566
201-206
2004
Streptomyces carzinostaticus, Streptomyces carzinostaticus ATCC 15944
Manually annotated by BRENDA team