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2.3.1.235: tetracenomycin F2 synthase

This is an abbreviated version!
For detailed information about tetracenomycin F2 synthase, go to the full flat file.

Word Map on EC 2.3.1.235

Reaction

10 malonyl-CoA =

tetracenomycin F2
+ 10 CoA + 10 CO2 + 2 H2O

Synonyms

TCM F2, TCM PKS, TcmK protein, TcmN polyketide cyclase, type II polyketide synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.235 tetracenomycin F2 synthase

Reference

Reference on EC 2.3.1.235 - tetracenomycin F2 synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bao, W.; Wendt-Pienkowski, E.; Hutchinson, C.R.
Reconstitution of the iterative type II polyketide synthase for tetracenomycin F2 biosynthesis
Biochemistry
37
8132-8138
1998
Streptomyces glaucescens
Manually annotated by BRENDA team
Meurer, G.; Hutchinson, C.R.
Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens
J. Bacteriol.
177
477-481
1995
Streptomyces glaucescens (P16538), Streptomyces glaucescens
Manually annotated by BRENDA team
Shen, B.; Hutchinson, C.R.
Deciphering the mechanism for the assembly of aromatic polyketides by a bacterial polyketide synthase
Proc. Natl. Acad. Sci. USA
93
6600-6604
1996
Streptomyces glaucescens (P16559), Streptomyces glaucescens
Manually annotated by BRENDA team