2.1.1.259: [fructose-bisphosphate aldolase]-lysine N-methyltransferase
This is an abbreviated version!
For detailed information about [fructose-bisphosphate aldolase]-lysine N-methyltransferase, go to the full flat file.
Reaction
3 S-adenosyl-L-methionine + = 3 S-adenosyl-L-homocysteine +
Synonyms
chloroplastic protein methyltransferase, large subunit of Rubisco methyltransferase, large subunit Rubisco methyltransferase, LSMT, LSMT-L, protein-lysine methyltransferase-like, PsLSMT, rbcMT, Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase, Ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase, Rubisco methyltransferase, S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase
ECTree
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Substrates Products
Substrates Products on EC 2.1.1.259 - [fructose-bisphosphate aldolase]-lysine N-methyltransferase
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REACTION DIAGRAM
3 adenosyl-L-methionine + [Rubisco large subunit]-L-lysine
3 S-adenosyl-L-homocysteine + [Rubisco large subunit]-N6,N6,N6-trimethyl-L-lysine
3 S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-L-lysine394
3 S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine394
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?
3 S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase]-L-lysine
3 S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
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?
3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine
3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
3 S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-lysine
3 S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6,N6,N6-trimethyl-L-lysine
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-
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?
S-adenosyl-L-homocysteine + [large subunit of spinach Rubisco-human carbonic anhydrase II fusion protein]-L-lysine
S-adenosyl-L-homocysteine + [large subunit of spinach Rubisco-human carbonic anhydrase II fusion protein]-N6,N6,N6-trimethyl-L-lysine
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mutagenesis of lysine residues 8, 18 and 28 to either Arg or Ala does not affect methylation of Lys-14 by the enzyme, whereas mutagenesis of the Lys-14 methylation site abolishes methylation
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?
S-adenosyl-L-methionine + [acyl carrier protein I precursor]-L-lysine
S-adenosyl-L-homocysteine + [acyl carrier protein I precursor]-N6,N6,N6-trimethyl-L-lysine
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?
S-adenosyl-L-methionine + [fructose 1,6-bisphosphate aldolase]-L-lysine
S-adenosyl-L-homocysteine + [fructose 1,6-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
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the substrate is trimethylated at a conserved lysyl residue located close to the C terminus
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?
S-adenosyl-L-methionine + [gamma-tocopherol methyltransferase]-L-lysine
S-adenosyl-L-homocysteine + [gamma-tocopherol methyltransferase]-N6,N6,N6-trimethyl-L-lysine
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?
S-adenosyl-L-methionine + [granule-bound starch synthase I precursor]-L-lysine
S-adenosyl-L-homocysteine + [granule-bound starch synthase I precursor]-N6,N6,N6-trimethyl-L-lysine
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-
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?
S-adenosyl-L-methionine + [NAD(P)H-quinone oxidoreductase chain 5]-L-lysine
S-adenosyl-L-homocysteine + [NAD(P)H-quinone oxidoreductase chain 5]-N6,N6,N6-trimethyl-L-lysine
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?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit]-N6,N6,N6-trimethyl-L-lysine
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no natural substrate. The enzyme is able to interact with unmethylated Rubisco, but the complex is catalytically unproductive
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?
S-adenosyl-L-methionine + [Rubisco large subunit]-L-lysine
S-adenosyl-L-homocysteine + [Rubisco large subunit]-N6,N6,N6-trimethyl-L-lysine
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?
3 S-adenosyl-L-homocysteine + [Rubisco large subunit]-N6,N6,N6-trimethyl-L-lysine
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?
3 adenosyl-L-methionine + [Rubisco large subunit]-L-lysine
3 S-adenosyl-L-homocysteine + [Rubisco large subunit]-N6,N6,N6-trimethyl-L-lysine
i.e. RBCL
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?
3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
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?
3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine
3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
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?
?
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no trimethylation of the Rubisco large subunit by the enzyme from Arabidosis thaliana
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additional information
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no trimethylation of the Rubisco large subunit by the enzyme from Arabidosis thaliana
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