2.1.1.177: 23S rRNA (pseudouridine1915-N3)-methyltransferase
This is an abbreviated version!
For detailed information about 23S rRNA (pseudouridine1915-N3)-methyltransferase, go to the full flat file.
Reaction
Synonyms
m3Psi methyltransferase, pseudouridine methyltransferase, Psi1915-specific methyltransferase, RlmH, rRNA large subunit methyltransferase H, YbeA
ECTree
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Reaction
Reaction on EC 2.1.1.177 - 23S rRNA (pseudouridine1915-N3)-methyltransferase
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S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
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S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
mechanism: the enzyme docks into the ribosomal A site without encroaching into the P site. YbeA makes extensive interface contacts with both the 30S and 50S subunits to align its active site cofactor adjacent to nucleotide C1915